Evidence map›Paper›PMID 40506583›Full record

ArticlePediatric research2026

Prevention of unplanned extubation in neonates with silk tie securement.

Tetyana H Nesterenko, Firas Saker, Daniel Kubiak, John Dickson, Amanda L Sheppard, Nicole Saliba, Katherine L Fedor, Mohamed A Mohamed, Hany Aly

Abstract read
In one paragraph

Article in Pediatric research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tetyana H Nesterenko *Neonatology, Cleveland Clinic Children's Hospital, Cleveland, OH, USA.
Firas Saker *Neonatology, Cleveland Clinic Children's Hospital, Cleveland, OH, USA.
Daniel KubiakContinuous Improvement, Cleveland Clinic, Cleveland, OH, USA.
John DicksonNeonatology, Cleveland Clinic Children's Hospital, Cleveland, OH, USA.
Amanda L SheppardNeonatology, Cleveland Clinic Children's Hospital, Cleveland, OH, USA.
Nicole SalibaNeonatology, Cleveland Clinic Children's Hospital, Cleveland, OH, USA.
Katherine L FedorNeonatology, Cleveland Clinic Children's Hospital, Cleveland, OH, USA.
Mohamed A MohamedNeonatology, Cleveland Clinic Children's Hospital, Cleveland, OH, USA.
Hany AlyNeonatology, Cleveland Clinic Children's Hospital, Cleveland, OH, USA. alyh@ccf.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUnplanned extubation (UE) is the fourth most common adverse event in neonatal intensive care units (NICUs) and remains a significant global challenge. Standardizing endotracheal tube (ETT) maintenance could reduce UE rates to 0.5-1.0 events per 100 non-tracheostomy ventilation days. This quality improvement (QI) project aimed to reduce the UE rate to below 1.0 event per 100 non-tracheostomy ventilation days within 12 months.

methodsUsing a QI methodology, we conducted four Plan-Do-Study-Act (PDSA) cycles, including frequent ETT securement evaluations, ETT stabilization during procedures, audits of chest radiographs, and the use of a silk tie for ETT reinforcement. Statistical process control charts monitored progress.

resultsBaseline UE rate was 1.73 events per 100 non-tracheostomy ventilation days. The first three PDSA cycles (January 2019-May 2020) produced a non-significant signal for reduced UE to 0.88. After introducing the silk suture tie in PDSA cycle 4, the rate significantly declined to 0.58 and was sustained from October 2020 to December 2021. A further special cause variation occurred from February to December 2022 with UE reduction to 0.06.

conclusionsA multidisciplinary approach and silk suture tie intervention significantly reduced and sustained one of the lowest reported UE rates, enhancing ETT securement and patient safety. IMPACT: Unplanned extubation (UE) events are not uncommon in the neonatal intensive care unit. This project demonstrates that the lowest reported UE rates in neonatal ICUs are possible without incurring additional costs or requiring new securement devices. The success of this project underscores the importance of standardizing care, reducing variability, and fostering a multidisciplinary, collaborative approach. The silk tie enhancement for ETT stabilization offers a practical, scalable solution to prevent UEs and improve neonatal care.

Indexed as

Airway ExtubationIntubation, IntratrachealSilkSuturesFemaleHumansInfant, NewbornIntensive Care Units, NeonatalMaleQuality ImprovementRespiration, ArtificialSilk

Identifiers

PMID40506583
PMCPMC12956563

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.