Evidence map›Paper›PMID 40506567›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2025

Characterizing gait abnormalities in patients with symptomatic lumbar degenerative disc disease.

Ram Haddas, Haseeb E Goheer, Cindy Wang, Paul Rubery, Gabriel Ramirez, Varun Puvanesarajah

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Mapping the genetically predicted associations between lower-extremity muscle traits and spinal diseases.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  2. Clinical and biomechanical biomarkers of altered functional transitions in lumbar spinal stenosis with neurogenic claudication.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ram HaddasUniversity of Rochester Medical Center, Rochester, United States. Ram_Haddas@URMC.Rochester.edu.
Haseeb E GoheerUniversity of Rochester Medical Center, Rochester, United States.
Cindy WangUniversity of Rochester Medical Center, Rochester, United States.
Paul RuberyUniversity of Rochester Medical Center, Rochester, United States.
Gabriel RamirezUniversity of Rochester Medical Center, Rochester, United States.
Varun PuvanesarajahUniversity of Rochester Medical Center, Rochester, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo quantify and evaluate gait spatiotemporal and kinematic parameters in patients with symptomatic lumbar degeneration disc disease(LDD) with unilateral radiculopathy and/or neurogenic claudication.

methodsSeventy-eight pre-operative patients with LDD and 27 healthy adult volunteers were identified at a single institution. Participants were fitted with a full-body external reflective marker set for gait analysis using a three-dimensional motion capture system. Participants performed a series of over-ground walking trials at a self-selected speed. Spatiotemporal and kinematic parameters of gait were compared between cohorts using linear mixed-effects regression models.

resultsCompared with healthy participants, LDD patients had reduced cadence (101.3 steps/min vs. 110.9 steps/min, p < 0.001), step width (0.2 m vs. 0.1 m, p < 0.019), and step length (0.6 m vs. 0.7 m, p < 0.001). During the stance (ST) and swing (SW) phases of the gait cycle, LDD patients had significantly reduced hip extension (ST: 0.7° vs. 12.2° and SW: -7.6° vs. 3.8°) and sagittal plane hip range of motion (ST: 36.1° vs 42.5° and SW: 30.2° vs. 35.8°) on the symptomatic side compared to healthy subjects (p < 0.001). Furthermore, LDD patients had significantly greater anterior and posterior pelvic tilt when compared to healthy controls in both the swing and stance phases of the gait cycle.

conclusionPatients with LDD demonstrate significantly altered gait including reduced cadence and step-specific gait parameters compared to healthy controls. Additionally, LDD patients experienced modified hip excursion during both the swing and stance phases compared to healthy participants on the symptomatic side. This study comprehensively assesses clinically measurable spatiotemporal and kinematic gait parameters in patients with LDD and may provide further insight into disease-specific effects and compensatory mechanisms associated with symptomatic LDD.

Indexed as

GaitGait Disorders, NeurologicIntervertebral Disc DegenerationLumbar VertebraeAdultAgedBiomechanical PhenomenaFemaleGait AnalysisHumansMaleMiddle AgedRadiculopathyGaitGait analysisNeurogenic claudicationPatient-reported outcomes measurement information system (PROMIS)Spatiotemporal parametersUnilateral radiculopathy

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.