Evidence map›Paper›PMID 40506235›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2025

Dual-Tracer Imaging on a Long-Axial-Field-of-View PET: A Proof-of-Principle Study with [

Daniel Kwon, Elizabeth J Li, Christina Dulal, Margaret Daube-Witherspoon, Varsha Viswanath, Anthony J Young, Raheema A Damani, Jason Hou-Liu, Elizabeth S McDonald, David A Mankoff and 2 more

Abstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Metabolic Imaging and Molecular Signatures Reveal Metabolic Phenotypes in Recurrent Glioblastoma.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Daniel KwonDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania.
Elizabeth J LiDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania.
Christina DulalDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania.
Margaret Daube-WitherspoonDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania.
Varsha ViswanathDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania.
Anthony J YoungDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania.
Raheema A DamaniDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania.
Jason Hou-LiuDepartment of Statistics and Actuarial Science, University of Waterloo, Waterloo, Ontario, Canada.
Elizabeth S McDonaldDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania.
David A MankoffDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania.
Joel S KarpDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania.
Austin R PantelDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania; austin.pantel@pennmedicine.upenn.edu.

Funding

Time-of-Flight PET for Improved Whole-Body ImagingR01CA113941 · NCI · UNIVERSITY OF PENNSYLVANIA · PI JOEL S KARP, Suleman Surti · 2006 to 2026
$9.8M
Molecular Imaging Markers for Glutaminolysis in Breast CancerR01CA211337 · NCI · UNIVERSITY OF PENNSYLVANIA · PI MANKOFF, DAVID A., ZHOU, RONG · 2017 to 2021
$2.0M
Area B: Multi-Tracer Volumetric PET (MTV-PET) to Measure Tumor Glutamine and Glucose Metabolic Rates in a Single Imaging SessionR33CA225310 · NCI · UNIVERSITY OF PENNSYLVANIA · PI KARP, JOEL S, MANKOFF, DAVID A. · 2017 to 2017
$1.4M
NCI NIH HHS R01 CA113941NCI NIH HHS R01 CA211337NCI NIH HHS R33 CA225310
6 · The paper itself

Abstract

Current protocols necessitate imaging 2

Indexed as

Fluorodeoxyglucose F18Positron-Emission TomographyFemaleGlutamineHumansMaleProof of Concept StudyRadioactive TracersRadiopharmaceuticals4-fluoroglutamineFluorodeoxyglucose F18GlutamineRadioactive TracersRadiopharmaceuticalscancer metabolismdual-tracer PETdynamic PET imaginglong–axial-field-of-view PET/CTPET

Identifiers

PMID40506235
PMCPMC12212401

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.