Evidence map›Paper›PMID 40506226›Full record

ArticleTobacco control2025

Trends of oral nicotine pouch prices and sales by product characteristics in the USA, 2021-2024.

Yanun He, Zezhong Zhang, Brittney Keller-Hamilton, Darren Mays, Theodore L Wagener, Micah L Berman, Ce Shang

Abstract read
In one paragraph

Article in Tobacco control, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Trial
  2. Oral Nicotine Pouches and Public Health: Evidence from an Updated Scoping Review.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yanun HeCenter for Tobacco Research, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA Yanyun.he@osumc.edu.ORCID http://orcid.org/0000-0001-6279-6102
Zezhong ZhangCenter for Tobacco Research, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA.
Brittney Keller-HamiltonCenter for Tobacco Research, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA.ORCID http://orcid.org/0000-0002-8574-7263
Darren MaysCenter for Tobacco Research, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA.ORCID http://orcid.org/0000-0002-6605-0743
Theodore L WagenerCenter for Tobacco Research, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA.ORCID http://orcid.org/0000-0002-9072-228X
Micah L BermanCollege of Public Health, The Ohio State University, Columbus, Ohio, USA.ORCID http://orcid.org/0000-0002-0336-1317
Ce ShangCenter for Tobacco Research, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA.ORCID http://orcid.org/0000-0002-8838-4250

Funding

The Ohio State University Tobacco Center of Regulatory Science (OSU-TCORS)U54CA287392 · NCI · OHIO STATE UNIVERSITY · PI Peter G. Shields, Theodore Lee Wagener · 2023 to 2026
$19.5M
NCI NIH HHS U54 CA287392
6 · The paper itself

Abstract

backgroundOral nicotine pouches (ONPs) have rapidly gained popularity in recent years. While ONPs likely expose users to fewer toxicants than cigarettes, they contain nicotine and may initiate, sustain or increase nicotine addiction and dependence. Monitoring the ONP marketplace is essential to inform timely regulatory action.

methodsWe used Nielsen ScanTrack data to analyse ONP sales and prices from 2021 to 2024. Joinpoint regression assessed sales and price trends, and ordinary least squares regression evaluated the association between ONP sales and product characteristics.

resultsMonthly ONP unit sales increased significantly, from 327 million in July 2021 to 1046 million in May 2024-more than tripling over this period (p<0.001, average monthly per cent change (AMPC)=3.45). Inflation-adjusted prices also rose, from 19 cents/pouch in June 2021 to 22 cents/pouch in May 2024 (p<0.001, AMPC=0.50). The sales of ZYN, On!, Rogue and VELO account for 99.8% of total sales. ONPs with explicit flavour descriptors outsold those with implicit flavour descriptors by more than eight times. The 'chill' flavour had also gained notable popularity. ONPs with 6 mg and 3 mg nicotine concentrations made up 68% of total sales. Additionally, ONPs with explicit flavour descriptors and higher nicotine concentrations were associated with increased sales.

conclusionsPolicy-makers may need to consider the role of major manufacturers, product flavours, and nicotine content in shaping the market. Continued surveillance is warranted to assess trends in use, particularly among youth and non-tobacco users.

Indexed as

NicotinePriceSurveillance and monitoringTobacco industry

Identifiers

PMID40506226
PMCPMC12285603

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.