Evidence map›Paper›PMID 40506087›Full record

SynthesisBMJ paediatrics open2025

Environmental factors and clinical markers of stress during neonatal transport: a systematic literature review .

Tone Solvik-Olsen, Marit Bekkevold, Fridtjof Heyerdahl, Astri Maria Lang, Jostein S Hagemo, Marius Rehn

Abstract readSystematic Review
In one paragraph

Synthesis in BMJ paediatrics open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Data variables reported during neonatal transport: a systematic literature review.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tone Solvik-OlsenClinical Medicine, University of Oslo Faculty of Medicine, Oslo, Norway tone.solvik-olsen@norskluftambulanse.no.ORCID http://orcid.org/0009-0005-7261-4401
Marit BekkevoldNorwegian Air Ambulance Foundation, Oslo, Norway.ORCID http://orcid.org/0000-0003-3290-9465
Fridtjof HeyerdahlFaculty of Medicine, University of Oslo, Oslo, Norway.ORCID http://orcid.org/0000-0001-9602-4370
Astri Maria LangNeonatal Intensive Care Department, Oslo University Hospital, Oslo, Norway.ORCID http://orcid.org/0000-0002-6796-7668
Jostein S HagemoNorwegian Air Ambulance Foundation, Oslo, Norway.ORCID http://orcid.org/0000-0003-4420-5588
Marius RehnNorwegian Air Ambulance Foundation, Oslo, Norway.ORCID http://orcid.org/0000-0001-9519-241X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNeonatal transport is an essential component of modern neonatal intensive care globally, providing access to advanced treatment while exposing vulnerable neonates to environmental conditions that may increase the risk of physiological instability.

objectiveTo systematically review studies measuring environmental exposures, specifically vibration, sound and temperature fluctuations during neonatal transport and to evaluate their impact on clinical parameters in neonates.

methodsA systematic literature review identified studies reporting environmental factors or clinical data during transport via ground, rotor or fixed-wing air ambulances. The medical databases searched included MEDLINE/PubMed, Embase, the Cochrane database of systematic reviews, Nursing Reference Center Plus, UpToDate and SveMed covering the period from November 2020 to January 2025.

results15 observational studies, 13 prospective and 2 retrospective covering publications from 1992 to 2025 were included. The studies included data on vibration, sound, ambient temperature and a wide range of clinical parameters such as heart rate and heart rate variability, change in clinical behaviour scales and cortisol in saliva reflecting the neonatal condition. Only four articles reported the effect of environmental factors on neonatal physiology.

conclusionsThis review highlights the presence of environmental factors, particularly noise and vibration, during transport and raises concerns about their impact on neonates. Although diverse clinical parameters were documented, the small sample sizes and variability in measurement methods across studies limit the ability to draw definitive conclusions. These observations emphasise the need for standardised monitoring protocols and further research to optimise neonatal transport practices.

Indexed as

Environmental ExposureStress, PhysiologicalTransportation of PatientsHumansInfant, NewbornNoiseTemperatureVibrationHealth services researchNeonatologyTechnology

Identifiers

PMID40506087
PMCPMC12161348

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.