Evidence map›Paper›PMID 40506078›Full record

ArticleBMJ open2025

Comparison of percutaneous neuromodulation and therapeutic exercise in patients with chronic non-specific neck pain: a study protocol for a randomised controlled trial.

Inmaculada Carmen Lara-Palomo, Raúl Romero-Del Rey, Manuel Saavedra-Hernández, Héctor García-López, Manuel Fernandez-Sanchez, Steven Paul Cohen, Adelaida María Castro-Sánchez

Registry-linked trialAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06695949 (Comparison of Percutaneous Neuromodulation and Therapeutic Exercise in Patients With Nonspecific Chronic Neck Pain), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06695949 nacompletednot on this map

Comparison of Percutaneous Neuromodulation and Therapeutic Exercise in Patients With Nonspecific Chronic Neck Pain: A Randomized Clinical Trial

TypeinterventionalSponsorUniversidad de AlmeriaRan2025 to 2025Enrolled100ConditionsNeck Pain, Chronic PainArmsPercutaneous neuromodulation., Therapeutic Exercise.
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Inmaculada Carmen Lara-PalomoNursing, Physical Therapy and Medicine, University of Almeria, Almeria, Andalucía, Spain.
Raúl Romero-Del ReyNursing, Physical Therapy and Medicine, University of Almeria, Almeria, Andalucía, Spain rrd239@ual.es.ORCID http://orcid.org/0000-0002-5885-5218
Manuel Saavedra-HernándezNursing, Physical Therapy and Medicine, University of Almeria, Almeria, Andalucía, Spain.
Héctor García-LópezNursing, Physical Therapy and Medicine, University of Almeria, Almeria, Andalucía, Spain.
Manuel Fernandez-SanchezNursing, Physical Therapy and Medicine, University of Almeria, Almeria, Andalucía, Spain.ORCID http://orcid.org/0000-0001-9201-6285
Steven Paul CohenEdmond I. Eger Chair of Anesthesiology & Vice Chair of Research and Pain Medicine. Professor of Anesthesiology, Neurology, Physical Medicine & Rehabilitation, Psychiatry and Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Adelaida María Castro-SánchezNursing, Physical Therapy and Medicine, University of Almeria, Almeria, Andalucía, Spain.ORCID http://orcid.org/0000-0002-9607-3241

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNeck pain is highly prevalent worldwide with no reliable or approved therapies. Recently, percutaneous neuromodulation (PNM) has gained popularity as an alternative to conventional treatments for managing musculoskeletal disorders.

objectiveThis study aims to assess the comparative effectiveness of PNM compared with therapeutic exercise in the management of patients with chronic non-specific neck pain (CNNP). METHODS AND ANALYSIS: In this randomised, controlled, single-blind study, 100 patients with CNNP will be allocated in a 1:1 ratio into two study groups: treatment with PNM and treatment with therapeutic exercise (specific neck exercises). A total of 18 structured exercise sessions will be administered three times per week for 6 weeks. Disability, pain intensity, fear of movement, quality of life, quality of sleep, catastrophising, cervical range of motion and pressure pain threshold will be recorded at 6 weeks (immediately post-treatment) and 8 weeks after initiation (or the end of treatment). ETHICS AND DISSEMINATION: Ethical approval was obtained from the provincial research ethics committee of Almeria (AP-0429-2023 C4-F2) in June 2024. The results of the study, including feasibility outcomes, will be published in peer-reviewed journals and presented at academic, clinical and healthcare conferences. TRIAL REGISTRATION NUMBER: ClinicalTrials.gov: NCT06695949.

Indexed as

Chronic PainExercise TherapyNeck PainTranscutaneous Electric Nerve StimulationAdultFemaleHumansMaleMiddle AgedPain MeasurementQuality of LifeRandomized Controlled Trials as TopicSingle-Blind MethodTreatment OutcomeExerciseneck painpercutaneous neuromodulation

Identifiers

PMID40506078
PMCPMC12161351

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.