Evidence map›Paper›PMID 40505043›Full record

ArticleOptometry and vision science : official publication of the American Academy of Optometry2025

The effect of pupil size on visual performance with center-distance soft multifocal contact lenses.

Jackson C Dolce, Augustine N Nti, David A Berntsen

Abstract read
In one paragraph

Article in Optometry and vision science : official publication of the American Academy of Optometry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jackson C DolceUniversity of Houston College of Optometry, Houston, Texas.
Augustine N Nti
David A Berntsen

Funding

SHORT TERM TRAINING--STUDENTS IN HEALTH PROFESSIONST35EY007088 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI FRISHMAN, LAURA J. · 1985 to 2025
$2.3M
NEI NIH HHS T35 EY007088
6 · The paper itself

Abstract

significanceMultifocal contact lenses have been shown to slow myopia progression in children. Understanding their impact on visual performance is important. While these lenses have little effect on high-contrast visual acuity, they reduce low-contrast visual acuity and contrast sensitivity, with these reductions being greater as pupil size increases. PURPOSE: This study aimed to determine the effect of pupil size on visual performance with center-distance multifocal contact lenses used for myopia control.

methodsTwenty-four myopic, nonpresbyopic adults were fitted with a single vision (Biofinity) and a center-distance multifocal (Biofinity D +2.50 add) contact lens, in random order. The pupil was dilated, and visual acuity (high and low contrast) and contrast sensitivity were measured through a 3 and 6 mm aperture.

resultsVisual acuity differed by contrast level and depended on lens design and pupil size (p=0.0040). With both pupil sizes, high-contrast acuity with the multifocal lens was only two letters worse than with the single vision lens (p=0.0001). Lens design effects on low-contrast acuity were pupil size-dependent (p=0.0006). Compared with single vision lenses, low-contrast acuity with multifocal lenses was about three letters worse for a 3 mm pupil (mean ± standard error of the mean = 0.07 ± 0.02 logMAR, p=0.0010) and about two lines worse with a 6 mm pupil (0.19 ± 0.02 logMAR; p<0.001). While wearing the multifocal lens, low-contrast acuity decreased by nearly two lines when pupil size increased from 3 to 6 mm (0.17 ± 0.02 logMAR; p<0.0001). The effect of lens design on the area under the log contrast sensitivity function was pupil-size-dependent (p=0.024). When compared with a 3 mm pupil, the greatest reduction in area under the log contrast sensitivity function at the larger 6 mm pupil size was with the multifocal lens, causing a 17% decrease compared with a 9% decrease for the single vision lens (p<0.0001).

conclusionsMultifocal contact lenses perform similarly to single vision lenses under high-contrast and smaller pupil conditions; however, visual performance reductions increase with lower contrast and a larger pupil size.

Indexed as

Contact Lenses, HydrophilicContrast SensitivityMyopiaPupilRefraction, OcularVisual AcuityAdultEquipment DesignFemaleHumansMaleMiddle AgedYoung Adult

Identifiers

PMID40505043
PMCPMC13020428

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.