Evidence map›Paper›PMID 40504855›Full record

ArticlePloS one2025

Time to first antenatal care contact and pooled prevalence among reproductive-age women in East Africa: Log-logistic shared frailty model.

Simachew Getaneh Endalamew, Fetlework Gubena Arage, Asefa Adimasu Taddese, Dejen Kahsay Asgedom, Bewuketu Terefe, Solomon Keflie Assefa

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Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Simachew Getaneh EndalamewDepartment of Veterinary Epidemiology and Public Health, School of Veterinary Medicine, Bahir Dar University, Bahir Dar, Ethiopia.ORCID https://orcid.org/0009-0005-2692-7394
Fetlework Gubena ArageDepartment of Biostatistics and Epidemiology, Institute of Public Health, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.
Asefa Adimasu TaddeseDepartment of Biostatistics and Epidemiology, Institute of Public Health, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.ORCID https://orcid.org/0009-0005-6988-9471
Dejen Kahsay AsgedomDepartment of Public Health, College of Medicine and Health Science, Samara University, Samara, Ethiopia.
Bewuketu TerefeDepartment of Community Health Nursing, School of Nursing, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.
Solomon Keflie AssefaDepartment of Biostatistics and Epidemiology, Institute of Public Health, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAntenatal care (ANC), the provision of prenatal healthcare by skilled medical practitioners, is essential for ensuring the well-being of pregnant women and their fetuses. It reduces maternal and child morbidity and mortality. However, there is a lack of comprehensive, region-wide analyses of ANC initiation, particularly across diverse East African countries. Therefore, this study aimed to determine the time to first antenatal care and its associated factors in East African countries.

methodsDemographic and Health Survey (DHS) data from 2012-2022 consisting of 12 countries were extracted. A total of 93,213 weighted reproductive-age women (15-49 years) were included in this study. A Kaplan-Meier survivor curve was generated to estimate the time of the first antenatal care contact. A log-rank test was used to compare the difference in survival curves. The log-logistic gamma shared frailty model was selected based on the reduced Akaike and Bayesian Information Criteria, and Cox-Snell residual plot. The shared frailty model was utilized to capture the correlation of outcomes within clusters (countries), as individuals within the same country may experience similar risks.

resultsThe pooled prevalence of women with a minimum of 4 ANC contacts in East African countries was 57.7% (95% CI: (49.9-65.1%). The variability in effect sizes of ANC utilization across included countries is estimated at [Formula: see text] 0.2032 [95% CI: 0.1111-0.6611]. The overall median time to the first antenatal care contact was 4 months. The log-logistic shared frailty model showed that place of residence [ϕ = 1.014, 95% CI: (1.006, 1.021)], maternal age [ϕ = 0.978, 95% CI: (0.970, 0.980)], women's education level [ϕ = 0.964, 95% CI: (0.952, 0.971)], marital status [ϕ = 0.970, 95% CI: (0.963, 0.978)], wealth index [ϕ = 0.990, 95% CI: (0.982, 0.997)], healthcare distance [ϕ = 0.975, 95% CI: (0.969, 0.980)], and parity [ϕ = 1.111, 95% CI: (1.093, 1.129)] were significant determinants of time at first antenatal care visit.

conclusionWomen in East Africa initiated their first ANC visit later than the optimal period recommended by the World Health Organization (WHO). The positive correlation between early ANC initiation and access to media, healthcare access, and educational attainment may be utilized to promote increased early engagement in ANC services. Thus, governments and other responsible bodies should strive to implement programs to enhance access to healthcare and education, particularly for women living in rural areas, to improve the early initiation of antenatal care visits.

Indexed as

Prenatal CareAdolescentAdultAfrica, EasternFemaleHumansMiddle AgedPregnancyPrevalenceYoung Adult

Identifiers

PMID40504855
PMCPMC12161577

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.