Evidence map›Paper›PMID 40504780›Full record

ReviewPLoS neglected tropical diseases2025

Mpox in Africa: What we know and what is still lacking.

Jia Bainga Kangbai, Umaru Sesay, Ulrich Vickos, Fatmata Kagbanda, Mosoka Papa Fallah, Augustus Osborne

Abstract readReview
In one paragraph

Review in PLoS neglected tropical diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. In Critical Condition: The Urgent Need to Support Mpox Therapeutic and Diagnostic Pipelines.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Article
  7. Article
  8. Article
  9. Article
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  11. Article
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  14. The emergence of Mpox in Ethiopia: implications for public health action.Tropical diseases, travel medicine and vaccines · 2025
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jia Bainga KangbaiDepartment of Public Health, Njala University, Bo City, Sierra Leone.
Umaru SesaySierra Leone Field Epidemiology Training Program, National Public Health Agency, Freetown City, Sierra Leone.ORCID 0000-0002-6040-8660
Ulrich VickosLaboratory of Arbovirus, Haemorrhagic Fevers, Institute Pasteur de Bangui, Emerging Virus and Zoonosis, Bangui, Central African Republic.
Fatmata KagbandaDepartment of Public Health, Njala University, Bo City, Sierra Leone.
Mosoka Papa FallahAfrica Centres for Disease Control and Prevention, Addis Ababa, Ethiopia.
Augustus OsborneDepartment of Biological Sciences, Njala University, Bo City, Sierra Leone.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emerging as a major global health threat, Mpox previously known as Monkeypox has drawn attention due to a worrying surge in cases. This zoonotic disease, native to Central and West Africa, is marked by fever, rash, and lymphadenopathy and is primarily spread through direct contact with infected animals or people and indirectly through contaminated objects. Recent studies have indicated possible sexual transmission, underscoring how human behavior and environmental changes are increasing its prevalence, even though human-to-human transmission is less efficient than that of smallpox. Mpox is endemic in several African countries, and currently, the infection has spread in non-endemic countries, including Rwanda, Uganda, and Kenya. Democratic Republic of Congo is the epicenter of the current Mpox outbreak. From January 1, 2022, to August 6, 2024, sixteen African countries reported Mpox outbreak. Several factors, including population immunity deficiencies and changes to the environment and ecology, have led to the widespread of Mpox in Africa. Challenges such as the fragile healthcare system, limited vaccine availability and access, weak surveillance, and low public awareness poses difficulty in containing the infection in affected countries. Given the potential of Mpox to disrupt several sectors including health systems, which may ultimately reverse progress in achieving the sustainable development goals by 2030. It is imperative for countries, both within and outside Africa, to extend financial aid and human resources to combat the infection effectively.

Indexed as

Mpox, MonkeypoxAfricaAnimalsDisease OutbreaksHumansMonkeypox virusZoonoses

Identifiers

PMID40504780
PMCPMC12161565

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.