Evidence map›Paper›PMID 40504426›Full record

Observational studyJapanese journal of ophthalmology2025

Quantitative evaluation of inflammation after phacoemulsification surgery: anterior chamber flare and choroidal vascular index.

Metehan Simsek, Gulay Yalcınkaya Cakir, Efe Koser, Cigdem Altan, Muhittin Taşkapılı

Abstract readObservational Study
In one paragraph

Observational study in Japanese journal of ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Metehan SimsekDepartment of Ophthalmology, Beyoglu Eye Training and Research Hospital, University of Health Sciences, Istanbul, Turkey. metesimsek04@gmail.com.ORCID http://orcid.org/0000-0002-5348-9829
Gulay Yalcınkaya CakirDepartment of Ophthalmology, Beyoglu Eye Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.ORCID http://orcid.org/0000-0001-6248-5902
Efe KoserDepartment of Ophthalmology, Beyoglu Eye Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.ORCID http://orcid.org/0000-0001-9750-0092
Cigdem AltanDepartment of Ophthalmology, Beyoglu Eye Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-0908-6619
Muhittin TaşkapılıDepartment of Ophthalmology, Beyoglu Eye Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-3089-7782

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the relationship between phacoparameters and inflammation parameters (anterior chamber flare (ACF), macular and peripapillary choroidal vascular index (mCVI and pCVI)) changes after cataract surgery. STUDY

designProspective study

methodsThis prospective observational study included patients without systemic and ocular diseases who underwent uncomplicated cataract surgery that may have affected intraocular inflammation. Preoperative, postoperative 1st week, 1st, 3rd and 6th months ACF were measured. At the same visits, mCVI and pCVI were calculated. The relationship between phacoparameters and postoperative ACF, mCVI and pCVI values were evaluated by correlation analysis.

resultsFifty eyes of 50 patients were included in the study. Postoperative 1st week ACF was significantly higher than preoperative ACF (p<0.001). ACF decreased significantly from postoperative 1st week to 6th months. Postoperative 1st month and 3rd month mCVI were significantly higher than preoperative mCVI (p<0.001, p=0.04, respectively). It was observed that pCVI reached its peak value in the 1st postoperative week and decreased to base value in the postoperative 6th month. A strong positive linear correlation was found between total cumulative dissipated energy (CDE) and the difference between postoperative 1st week and preoperative ACF (p<0.001, r=0.68).

conclusionParticularly in the early period after phacoemulsification, ACF, mCVI and pCVI increased. The increase in ACF lost its significance at the third month and the increase in mCVI and pCVI remained significant, which may indicate that the inflammatory effect of cataract surgery lasts longer in the posterior segment. Total CDE can be used to predict postoperative inflammation levels.

Indexed as

Anterior ChamberChoroidPhacoemulsificationPostoperative ComplicationsAgedFemaleFluorescein AngiographyFollow-Up StudiesHumansMaleMiddle AgedProspective StudiesTomography, Optical CoherenceVisual AcuityAnterior chamber flareChoroidal vascular indexPhacoemulsification

Identifiers

PMID40504426
PMCPMC12391188

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.