Evidence map›Paper›PMID 40504251›Full record

ReviewPediatric surgery international2025

Cancer surveillance in biliary atresia patients with native liver survival: Standardizing monitoring and follow-up.

Omid Madadi-Sanjani, Lutz Fischer, Marie Uecker, Christian Tomuschat, Uta Herden, Martina Sterneck, Bianca Hegen

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Pediatric surgery international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Omid Madadi-SanjaniDepartment of Visceral Transplantation, University Medical Center Hamburg-Eppendorf, Martinistreet 52, 20251, Hamburg, Germany. o.madadi-sanjani@uke.de.
Lutz FischerDepartment of Visceral Transplantation, University Medical Center Hamburg-Eppendorf, Martinistreet 52, 20251, Hamburg, Germany.
Marie UeckerDepartment of Pediatric Surgery, Hannover Medical School, Hannover, Germany.
Christian TomuschatDepartment of Pediatric Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Uta HerdenDepartment of Visceral Transplantation, University Medical Center Hamburg-Eppendorf, Martinistreet 52, 20251, Hamburg, Germany.
Martina SterneckI. Department of Internal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Bianca HegenDepartment of Pediatric Gastroenterology and Hepatology, University Childrens Hospital, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biliary atresia (BA) is a rare cholangiopathy in neonates, leading to end-stage liver failure in the first years of life, when left untreated. Kasai procedure aims to restore biliary drainage to achieve native liver survival. While liver transplantation is the necessary treatment in children with failure of the Kasai procedure, the number of native liver survivors in the long-term remains around 20-30%. Reports on malignancies in native livers of children, adolescents and adults with BA are increasing, including cases of hepatocellular carcinoma, cholangiocarcinoma, hepatoblastoma and small intestinal adenocarcinoma. In this review we summarize the reports, with focus on tumor markers, imaging technologies and reported outcomes. Furthermore, we discuss recent advances in surveillance strategies in adults with chronic liver impairment.

Indexed as

Biliary AtresiaLiver NeoplasmsFollow-Up StudiesHumansInfant, NewbornPortoenterostomy, HepaticBiliary atresiaCholangiocarcinomaHepatoblastomaHepatocellular carcinomaNative liver survival

Identifiers

PMID40504251
PMCPMC12162786

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.