ReviewArchives of gynecology and obstetrics2025
Platelet-rich plasma therapy for thin endometrium: a comprehensive review.
Review in Archives of gynecology and obstetrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Platelet-rich plasma as an adjuvant therapy for intrauterine adhesions: a narrative review of mechanisms, clinical efficacy and combination strategies.Annals of medicine · 2026Review
- Platelet-Rich Plasma in Recurrent Pregnancy Loss: Toward a Precision Medicine Framework for Biologically Guided Patient Selection.Medical sciences (Basel, Switzerland) · 2026Review
- Endometrial Repair and Regenerative Medicine: From Broad-Spectrum Regeneration to Precision Intervention.Reproductive sciences (Thousand Oaks, Calif.) · 2026Review
- Intrauterine platelet-rich plasma and subsequent endometrial pathology evaluation in a patient undergoing a frozen embryo transfer cycle: a case report.Journal of assisted reproduction and genetics · 2026Article
- Impact of intrauterine infusion of human umbilical cord blood mononuclear cells on reproductive outcomes in patients with thin endometrium undergoing frozen embryo transfer.Frontiers in cell and developmental biology · 2026Article
- Endometrial receptivity failure in assisted reproduction: immune-cellular niches, mechanistic evidence, and translational boundaries.Frontiers in immunology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThin endometrium (TE) is a significant limiting factor for successful in vitro fertilization (IVF) and embryo transfer (ET), often resulting in poor pregnancy outcomes. Current therapeutic options remain limited and inconsistent in efficacy.
objectiveThis review aims to comprehensively evaluate the clinical potential of platelet-rich plasma (PRP) therapy as an emerging treatment to improve endometrial thickness and fertility outcomes in patients with TE.
methodsA systematic analysis of recent studies was conducted to summarize advancements in PRP application for TE. This includes evaluating PRP preparation techniques, treatment protocols, and reported clinical outcomes. Mechanistic insights into how PRP promotes endometrial regeneration through growth factors and angiogenesis were also explored.
resultsEvidence from current literature suggests that intrauterine infusion of PRP may enhance endometrial thickness and improve implantation and pregnancy rates in women with refractory TE. However, variations in PRP preparation methods and treatment protocols limit the comparability of results. Safety profiles appear favorable, with few reported adverse events.
conclusionPRP therapy holds promise as a regenerative approach for the treatment of TE. Nonetheless, the lack of standardized protocols and robust randomized controlled trials necessitates further research. Establishing consensus on preparation methods and treatment timing will be crucial for translating PRP therapy into routine clinical practice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.