Evidence map›Paper›PMID 40503888›Full record

ArticleApplied and environmental microbiology2025

Insights into genetic determinants of volatile fatty acid catabolism in

Eric C Holmes, Stephanie L Breunig, Christopher W Johnson, Gregg T Beckham, Alissa C Bleem

Abstract read
In one paragraph

Article in Applied and environmental microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Advances in the biological production of butyric acid.World journal of microbiology & biotechnology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Eric C HolmesRenewable Resources and Enabling Sciences Center, National Renewable Energy Laboratory, Golden, Colorado, USA.ORCID 0000-0001-5637-0404
Stephanie L BreunigRenewable Resources and Enabling Sciences Center, National Renewable Energy Laboratory, Golden, Colorado, USA.
Christopher W JohnsonRenewable Resources and Enabling Sciences Center, National Renewable Energy Laboratory, Golden, Colorado, USA.
Gregg T BeckhamRenewable Resources and Enabling Sciences Center, National Renewable Energy Laboratory, Golden, Colorado, USA.ORCID 0000-0002-3480-212X
Alissa C BleemRenewable Resources and Enabling Sciences Center, National Renewable Energy Laboratory, Golden, Colorado, USA.ORCID 0000-0003-1586-2554

Funding

Biological and Environmental Research DE-SC0023278National Renewable Energy Laboratory Laboratory Directed Research and Development (LDRD) Program
6 · The paper itself

Abstract

The soil bacterium IMPORTANCE: The development of efficient bioprocesses that utilize waste-derived carbon will be important for ensuring the circularity of carbon flows and the sustainability of new biotechnologies. Unfortunately, carbon substrates that can be reliably sourced from waste are often toxic or inefficient growth substrates for industrially relevant bacteria. A more complete understanding of the regulatory and biochemical mechanisms that bacteria use to respond to and catabolize waste-derived carbon resources will enable metabolic engineering strategies to improve bioconversion of these same resources. In this study, we provide new insight into these mechanisms for an emerging and promising host-feedstock pairing:

Indexed as

Bacterial ProteinsCupriavidus necatorFatty Acids, VolatileMetabolic Networks and PathwaysMultigene FamilyBacterial ProteinsFatty Acids, Volatileacyl-CoA synthetaseCupriavidus necatorfatty acid metabolismgene regulationmetabolic engineeringwaste valorization

Identifiers

PMID40503888
PMCPMC12285253

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.