Evidence map›Paper›PMID 40503834›Full record

ArticleMicrobiology spectrum2025

Distinct molecular characteristics and virulence profiles of carbapenem-resistant

Xiaodan Zhu, Pan Fu, Songzhen Yang, Wenjie Wang, Wenjing Ying, Bijun Sun, Jinqiao Sun, Chuanqing Wang, Qinhua Zhou, Xiaochuan Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xiaodan Zhu *Department of Clinical Immunology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.
Pan Fu *Department of Clinical Microbiology Laboratory, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.ORCID 0000-0003-2587-4348
Songzhen YangDepartment of Clinical Immunology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.
Wenjie WangDepartment of Clinical Immunology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.
Wenjing YingDepartment of Clinical Immunology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.
Bijun SunDepartment of Clinical Immunology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.
Jinqiao SunDepartment of Clinical Immunology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.
Chuanqing WangDepartment of Clinical Microbiology Laboratory, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.ORCID 0000-0002-0158-9094
Qinhua ZhouDepartment of Clinical Immunology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.ORCID 0000-0002-5112-3727
Xiaochuan WangDepartment of Clinical Immunology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.ORCID 0000-0003-3768-324X

Funding

National Natural Science Foundation of China 81501419Shanghai Science and Technology Development Foundation ZD2021CY001
6 · The paper itself

Abstract

Bacterial infections, especially multidrug-resistant Gram-negative bacterial infections, pose a great threat to patients with inborn errors of immunity (IEIs). This study investigates the molecular and virulence profiles of carbapenem-resistant IMPORTANCE: Bacterial infection, especially drug-resistant bacterial infection, poses a great risk to patients with IEIs. Antimicrobial resistance, particularly in pediatric patients, is a growing global health threat. Bacteria undergo a series of adaptive changes in response to pressures from the host. Patients with IEI provide a unique immune environment that may profoundly influence the molecular characteristics of bacterial pathogens. However, little is known about the molecular and virulence profiles of carbapenem-resistant

Indexed as

Acinetobacter baumanniiEnterobacter cloacaeEscherichia coliAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasesCarbapenemsDrug Resistance, Multiple, BacterialEnterobacteriaceae InfectionsFemaleHumansMaleMicrobial Sensitivity TestsVirulenceVirulence FactorsWhole Genome SequencingAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasesCarbapenemsVirulence FactorsAcinetobacter baumanniiCarbapenem-resistantChildrenEnterobacter cloacaeEscherichia coliInborn errors of immunity

Identifiers

PMID40503834
PMCPMC12323661

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.