Evidence map›Paper›PMID 40503832›Full record

ArticleMicrobiology spectrum2025

Yumiko Saito-Nakano, Shinji Izumiyama, Makoto Hirai, Tetsuro Kawano-Sugaya, Ghulam Jeelani, Sanjib K Sardar, Sandipan Ganguly, Tomoyoshi Nozaki

Abstract read
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yumiko Saito-NakanoDepartment of Parasitology, National Institute of Infectious Diseases, Japan Institute for Health Security, Shinjuku, Tokyo, Japan.ORCID 0000-0002-7132-194X
Shinji IzumiyamaDepartment of Parasitology, National Institute of Infectious Diseases, Japan Institute for Health Security, Shinjuku, Tokyo, Japan.
Makoto HiraiDepartment of Tropical Medicine and Parasitology, Faculty of Medicine, Juntendo University, Bunkyo, Tokyo, Japan.ORCID 0000-0002-5001-9653
Tetsuro Kawano-SugayaDepartment of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, Bunkyo, Tokyo, Japan.
Ghulam JeelaniDepartment of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, Bunkyo, Tokyo, Japan.
Sanjib K SardarDepartment of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, Bunkyo, Tokyo, Japan.
Sandipan GangulyDivision of Parasitology, ICMR-National Institute for Research in Bacterial Infections, Kolkata, West Bengal, India.
Tomoyoshi NozakiDepartment of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, Bunkyo, Tokyo, Japan.ORCID 0000-0003-1354-5133

Funding

Japan Agency for Medical Research and Development JP23fk0108680Japan Agency for Medical Research and Development JP23fk0108680 JP23jm0110022 JP233fa627001Japan Agency for Medical Research and Development JP23fk0108683 JP23fk0108680Japan Society for the Promotion of Science JP21H02723 JP21K19372 JP21KK135 JP21H04779Japan Society for the Promotion of Science JP22K07050
6 · The paper itself

Abstract

In drug discovery, target identification and elucidation of resistance mechanisms are essential. The pathogen strains resistant to a compound of interest are useful for these purposes. As the generation of drug-resistant strains is time-consuming and often burdensome, we generated the IMPORTANCE: The protozoan parasite

Indexed as

Antiprotozoal AgentsDrug ResistanceEntamoeba histolyticaMutationPhosphorylcholineDNA Polymerase IIIGenome, ProtozoanHumansMutation RateProtozoan ProteinsTetracyclineWhole Genome SequencingAntiprotozoal AgentsDNA Polymerase IIImiltefosinePhosphorylcholineProtozoan ProteinsTetracyclinedrug resistanceEntamoeba histolyticaerror-prone DNA polymerasemiltefosinemutator

Identifiers

PMID40503832
PMCPMC12323330

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.