Evidence map›Paper›PMID 40503773›Full record

ArticleBiomarkers in medicine2025

The relationship of serum lactate level with in-hospital mortality after transcatheter aortic valve implantation.

Osman Uzman, Murat Bastopcu, Mehmet Saygı, Koray Kalenderoğlu, Koray Demir, Kıvanç Keskin, Sait Terzi

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Article in Biomarkers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Osman UzmanDepartment of Cardiology, Health Sciences University, Dr Siyami Ersek Cardiovascular and Thoracic Surgery Center, Istanbul, Turkey.
Murat BastopcuDepartment of Cardiology, Health Sciences University, Dr Siyami Ersek Cardiovascular and Thoracic Surgery Center, Istanbul, Turkey.
Mehmet SaygıDepartment of Cardiology, Hisar Intercontinental Hospital, Istanbul, Turkey.
Koray KalenderoğluDepartment of Cardiology, Health Sciences University, Dr Siyami Ersek Cardiovascular and Thoracic Surgery Center, Istanbul, Turkey.
Koray DemirDepartment of Cardiology, Health Sciences University, Dr Siyami Ersek Cardiovascular and Thoracic Surgery Center, Istanbul, Turkey.
Kıvanç KeskinDepartment of Cardiology, Yuksekova State Hospital, Hakkari, Turkey.
Sait TerziDepartment of Cardiology, Health Sciences University, Dr Siyami Ersek Cardiovascular and Thoracic Surgery Center, Istanbul, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study assesses the influence of early hyperlactatemia after the transcatheter aortic valve implantation (TAVI) procedure on subsequent outcomes.

methodsAdult patients undergoing elective percutaneous TAVI between 2012 and 2022 in a single tertiary cardiac center were retrospectively included. Peak post-procedure lactate level within 24-h was recorded for 284 patients included in the study. The primary outcome measured was 30-day mortality.

results19 patients (6.6%) experienced 30-day mortality. Patients with mortality were characterized by advanced age (

conclusionThe initial 24-hour lactate levels seem to play a valuable role in predicting the likelihood of surviving during the hospital stay after the implantation procedure. Further investigation is required to ascertain the optimal strategies for managing early post-procedure hyperlactatemia in the TAVI population.

Indexed as

Hospital MortalityLactic AcidTranscatheter Aortic Valve ReplacementAgedAged, 80 and overAortic Valve StenosisFemaleHumansMaleRetrospective StudiesROC CurveLactic Acidaortic valve stenosislactatemortalityTranscatheter aortic valve implantationtranscatheter aortic valve replacement

Identifiers

PMID40503773
PMCPMC12184198

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.