Evidence map›Paper›PMID 40503759›Full record

ArticlePediatric dermatology

The Association of Psoriasis and Bacterial Infections in Pediatric Patients: A Retrospective Review.

Manisha Ravi, Kelly M Cordoro, Kristen E Holland, Carmel Aghdasi, Caden Ulschmid, Irene Lara-Corrales, Lucia Z Diaz, Courtney N Haller, Fabiana Castro Porto Silva Lopes, Lara Wine-Lee and 3 more

Abstract readMulticenter Study
In one paragraph

Article in Pediatric dermatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Manisha RaviThe Ohio State University and Nationwide Children's Hospital, Columbus, Ohio, USA.ORCID https://orcid.org/0000-0002-9047-4706
Kelly M CordoroSan Francisco Division of Pediatric Dermatology, University of California, San Francisco, California, USA.
Kristen E HollandMedical College of Wisconsin, Milwaukee, Wisconsin, USA.ORCID https://orcid.org/0000-0002-1851-5868
Carmel AghdasiSan Francisco Division of Pediatric Dermatology, University of California, San Francisco, California, USA.
Caden UlschmidIndiana University, Indianapolis, Indiana, USA.ORCID https://orcid.org/0000-0003-4519-5342
Irene Lara-CorralesHospital for Sick Children/University of Toronto, Toronto, Ontario, Canada.
Lucia Z DiazDell Children's Medical Center, Austin, Texas, USA.
Courtney N HallerDivision of Dermatology, The University of Texas at Austin-Dell Medical School, Austin, Texas, USA.
Fabiana Castro Porto Silva LopesDivision of Dermatology, The University of Texas at Austin-Dell Medical School, Austin, Texas, USA.ORCID https://orcid.org/0000-0003-1495-7519
Lara Wine-LeeMedical University of South Carolina Shawn Jenkins Children's Hospital, Charleston, South Carolina, USA.ORCID https://orcid.org/0000-0002-4175-316X
Caroline BrailsfordMedical University of South Carolina Shawn Jenkins Children's Hospital, Charleston, South Carolina, USA.
Amy Buros-SteinPediatric Dermatology Research Alliance, Portland, Oregon, USA.
Esteban Fernandez FaithThe Ohio State University and Nationwide Children's Hospital, Columbus, Ohio, USA.ORCID https://orcid.org/0000-0002-8641-6730

Funding

Pediatric Dermatology Research Alliance
6 · The paper itself

Abstract

BACKGROUND/

objectivesGuttate psoriasis onset and plaque psoriasis flares are associated with streptococcal pharyngitis. Literature regarding the relationship between anogenital bacterial dermatitis and psoriasis in pediatric patients is limited. We aimed to evaluate the clinical characteristics, microbiology, and treatment course of patients with psoriasis/psoriasiform dermatitis and concomitant pharyngeal and/or anogenital bacterial infections.

methodsA multicenter retrospective review of patients ≤ 18 years of age with psoriasis/psoriasiform dermatitis and bacterial infection, defined by positive culture results, was performed. Demographic characteristics, clinical features, microbiology, treatment recommendations, and outcomes were evaluated. Comparisons were made between pharyngeal and anogenital culture groups.

resultsA total of 166 unique patients with psoriasis/psoriasiform dermatitis and suspected pharyngeal and/or anogenital infection were evaluated between 2011 and 2021. Staphylococcus sp. and Streptococcus sp. were isolated in anogenital cultures. Inverse psoriasis was associated with a positive anogenital culture (p = 0.0356). Guttate psoriasis was more common in patients with a positive pharyngeal culture (p < 0.0001). Treatment of a positive bacterial culture did not correlate with the treatment response of psoriasis/psoriasiform dermatitis.

conclusionsInvestigations for anogenital and pharyngeal infections should be considered in pediatric patients presenting with new-onset or worsening psoriasis. A high clinical suspicion should be maintained for anogenital infection in patients with inverse psoriasis, specifically.

Indexed as

PharyngitisPsoriasisStreptococcal InfectionsAdolescentChildChild, PreschoolFemaleHumansInfantMaleRetrospective Studiesinfectionperianalpharyngealpsoriasiform dermatitispsoriasis

Identifiers

PMID40503759
PMCPMC12285559

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.