Evidence map›Paper›PMID 40503710›Full record

ArticleFuture science OA2025

Spectrophotometric analysis of artesunate injections available in community pharmacies in Northern and Western Uganda.

Ebere Emilia Ayogu, Emmanuel Aryon Ngolryeko, Joseph Obiezu Chukwujekwu Ezeonwumelu, Ibrahim Garba Wawata, Bashir Olaniyi Sadiq

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Future science OA, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ebere Emilia AyoguDepartment of Clinical Pharmacy and Pharmacy Practice, School of Pharmacy, Kampala International University, Ishaka, Bushenyi, Uganda.ORCID 0000-0003-1815-9821
Emmanuel Aryon NgolryekoDepartment of Clinical Pharmacy and Pharmacy Practice, School of Pharmacy, Kampala International University, Ishaka, Bushenyi, Uganda.
Joseph Obiezu Chukwujekwu EzeonwumeluDepartment of Clinical Pharmacy and Pharmacy Practice, School of Pharmacy, Kampala International University, Ishaka, Bushenyi, Uganda.
Ibrahim Garba WawataInstitute of Biomedical Research, Kampala International University, Ishaka, Bushenyi, Uganda.
Bashir Olaniyi SadiqDepartment of Computer Engineering, Kampala International University, Ishaka, Bushenyi, Uganda.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe surge in different brands of artesunate injection in Uganda, has raised the need for this study, which aimed at quantifying the actual amount of artesunate in different brands of artesunate injections available in Northern and Western Uganda. MATERIALS AND

methodsThe wavelength at maximum absorbance of pure artesunate powder was determined using Ultraviolet-visible spectrophotometer and Beer Lambert's plot was generated. This was validated and used to assay 27 brands of artesunate.

resultsIn the spectrophotometric assay method used, Beer Lambert's law was obeyed within the range of 20 µg/ml-140 µg/ml with linear regression equation of y = 0.012 + 0.030 and correlation coefficient of (R

conclusionMost brands of artesunate injection assayed deviated from labeled claim, regional/environmental factor impacted much on the stability of artesunate thus there is need for further screening of the quality of artesunate injection in circulation in view of the therapeutic consequences of substandard artesunate injection.

Indexed as

Artesunate injectiondrug quality assessmentsevere malaria treatmentspectrophotometric analysisUganda malaria burden

Identifiers

PMID40503710
PMCPMC12164379

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.