Evidence map›Paper›PMID 40503400›Full record

ArticleWorld journal of clinical oncology2025

Homeobox C6 plays an oncogenic role in bladder cancer.

Ding-Jin Lu, Hai-Rong Wang, You-Sheng Xu, Hai-Bo Huang, Qi-Gang Zhong, Yuan-Ning Luo, Jian-Feng Qi, Hong-Chao Wu, Jin-Ye Pei, Kun Zhang and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of clinical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Ding-Jin LuDepartment of Urology, Beihai People's Hospital, Beihai 536000, Guangxi Zhuang Autonomous Region, China.
Hai-Rong WangDepartment of Urology, Beihai People's Hospital, Beihai 536000, Guangxi Zhuang Autonomous Region, China.
You-Sheng XuDepartment of Urology, Beihai People's Hospital, Beihai 536000, Guangxi Zhuang Autonomous Region, China.
Hai-Bo HuangDepartment of Urology, Beihai People's Hospital, Beihai 536000, Guangxi Zhuang Autonomous Region, China.
Qi-Gang ZhongDepartment of Urology, Beihai People's Hospital, Beihai 536000, Guangxi Zhuang Autonomous Region, China.
Yuan-Ning LuoDepartment of Urology, Beihai People's Hospital, Beihai 536000, Guangxi Zhuang Autonomous Region, China.
Jian-Feng QiDepartment of Urology, Beihai People's Hospital, Beihai 536000, Guangxi Zhuang Autonomous Region, China.
Hong-Chao WuDepartment of Urology, Beihai People's Hospital, Beihai 536000, Guangxi Zhuang Autonomous Region, China.
Jin-Ye PeiDepartment of Urology, Beihai People's Hospital, Beihai 536000, Guangxi Zhuang Autonomous Region, China.
Kun ZhangDepartment of Urology, Beihai People's Hospital, Beihai 536000, Guangxi Zhuang Autonomous Region, China.
Chao-Xiong XuDepartment of Pathology, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China.
Tian-Xian WangDepartment of Pathology, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China.
Wei ZhangDepartment of Pathology, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China.
Yu-Hong ZhouDepartment of Pathology, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China.
Zhi-Guang HuangDepartment of Pathology, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China.
Fu-Bo WangCenter for Genomic and Personalized Medicine, Guangxi Key Laboratory for Genomic and Personalized Medicine, Guangxi Collaborative Innovation Center for Genomic and Personalized Medicine, University Engineering Research Center of Digital Medicine and Healthcare, Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBladder cancer (BLCA) is a common urological tumor. Homeobox C6 (

aimTo investigate the expression and function of

methodsThis study employed immunohistochemistry, along with global chip and sequencing data for BLCA, to comprehensively evaluate the protein and mRNA expression of

resultsThe immunohistochemistry results, sequencing data, and microarray data revealed that both the mRNA and protein expressions of

conclusion

Indexed as

Bladder cancerCellular functionHomeobox C6Timeless circadian regulatorTranscriptional regulation

Identifiers

PMID40503400
PMCPMC12149837

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.