Evidence map›Paper›PMID 40503359›Full record

ReviewWorld journal of stem cells2025

Circular RNAs inducing the osteogenic differentiation of dental mesenchymal stem cells

Yong-Song Jiang, Wei-Sheng Wei, Dao-Tao Xie, Gang Guo

Abstract readReview
In one paragraph

Review in World journal of stem cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yong-Song JiangDepartment of Orthopedic, The Central Hospital of Yongzhou, Yongzhou 425000, Hunan Province, China.
Wei-Sheng WeiDepartment of Orthopedic, The Central Hospital of Yongzhou, Yongzhou 425000, Hunan Province, China.
Dao-Tao XieNorxin International Technology Innovation Cooperation Platform, Xi'an 710032, Shaanxi Province, China. daotaoxie@gmail.com.
Gang GuoNorxin International Technology Innovation Cooperation Platform, Xi'an 710032, Shaanxi Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circular RNAs (circRNAs) are a distinct type of nonlinear and noncoding RNAs endogenously expressed by pre-mRNA back-splicing and crucial in transcriptional and posttranscriptional regulation. CircRNAs can regulate cellular and molecular pathways through various mechanisms, such as microRNA sponging. Numerous studies have indicated the regulatory roles of circRNAs in the osteogenic differentiation of stem cells (SCs) isolated from different sources. Dental tissue-derived mesenchymal SCs (MSCs) have received considerable attention in artificial bone engineering, in which SCs are used to manufacture functional bone tissues to repair bone defects. Recently, studies have reported the regulatory roles of circRNAs in the osteogenic differentiation of dental-derived MSCs, such as apical papillae, dental pulp, and dental follicle SCs. This review aimed to discuss the findings of studies evaluating the contribution of circRNAs to the osteogenic differentiation of dental-derived MSCs.

Indexed as

Circular RNADental stem cellsDentistryMicroRNAOsteogenesis

Identifiers

PMID40503359
PMCPMC12149794

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.