Evidence map›Paper›PMID 40503306›Full record

ArticleRSC advances2025

Photothermal therapeutic effects and biosafety of a carbon nanoparticles-Fe(ii) complex for triple-negative breast cancer.

Yuanfang Huang, Kexin Tang, Guangfu Zeng, Huahui Yuan, Qian Xin, Yufeng Zhao, Ting Qu, Jinmei Yang, Cheng Zeng, Xian Wu and 4 more

Abstract read
In one paragraph

Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yuanfang HuangSichuan Enray Pharmaceutical Sciences Company Chengdu 610041 China pharmmateceo@enraypharm.com.
Kexin TangSichuan Enray Pharmaceutical Sciences Company Chengdu 610041 China pharmmateceo@enraypharm.com.
Guangfu ZengSichuan Enray Pharmaceutical Sciences Company Chengdu 610041 China pharmmateceo@enraypharm.com.
Huahui YuanSichuan Enray Pharmaceutical Sciences Company Chengdu 610041 China pharmmateceo@enraypharm.com.
Qian XinSichuan Enray Pharmaceutical Sciences Company Chengdu 610041 China pharmmateceo@enraypharm.com.
Yufeng ZhaoSichuan Enray Pharmaceutical Sciences Company Chengdu 610041 China pharmmateceo@enraypharm.com.
Ting QuSichuan Enray Pharmaceutical Sciences Company Chengdu 610041 China pharmmateceo@enraypharm.com.
Jinmei YangSichuan Enray Pharmaceutical Sciences Company Chengdu 610041 China pharmmateceo@enraypharm.com.
Cheng ZengSichuan Enray Pharmaceutical Sciences Company Chengdu 610041 China pharmmateceo@enraypharm.com.
Xian WuSchool of Chemistry and Environment, Southwest Minzu University Chengdu 610041 China yangst@swun.edu.cn.
Zehui GouDepartment of Medical Ultrasound, West China Hospital/West China School of Medicine, Sichuan University Chengdu 610041 China.
Ping XieSichuan Enray Pharmaceutical Sciences Company Chengdu 610041 China pharmmateceo@enraypharm.com.
Sheng-Tao YangSchool of Chemistry and Environment, Southwest Minzu University Chengdu 610041 China yangst@swun.edu.cn.ORCID https://orcid.org/0000-0001-6795-8879
Xiaohai TangSichuan Enray Pharmaceutical Sciences Company Chengdu 610041 China pharmmateceo@enraypharm.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Triple-negative breast cancer (TNBC) has become a major challenge in clinical treatment due to its highly aggressive nature and limited therapeutic options. A carbon nanoparticles-Fe(ii) complex (CNSI-Fe), as both a ferroptosis inducer and photothermal agent (PTA), could exert anticancer effects through the ferroptosis pathway and photothermal action. Herein, we evaluated the photothermal therapeutic effects of CNSI-Fe in mice bearing the model tumor of TNBC (4T1 tumor). The therapeutic effects of CNSI-Fe were compared without/with near-infrared (NIR) irradiation both

Identifiers

PMID40503306
PMCPMC12150394

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.