Evidence map›Paper›PMID 40503189›Full record

ArticleGastroenterology research2025

Impact of Hospital Teaching Status on Outcomes of Acute Cholangitis: A Propensity-Matched Analysis of Hospitalizations in the United States.

Karan J Yagnik, Raj Patel, Sneh Sonaiya, Charmy Parikh, Pranav Patel, Yash Shah, Umar Hayat, Dushyant Singh Dahiya, Dhruvil Radadiya, Hareesha Rishab Bharadwaj and 5 more

Abstract read
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In one paragraph

Article in Gastroenterology research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Karan J YagnikDepartment of Medicine, Rutgers School of Medicine/Monmouth Medical Center, Long Branch, NJ 07740, USA.
Raj PatelDepartment of Medicine, St. Mary Medical Center, Langhorne, PA 19047, USA.
Sneh SonaiyaDepartment of Medicine, Kirk Kerkorian School of Medicine at UNLV, Las Vegas, NV 89102, USA.
Charmy ParikhDepartment of Medicine, Mercy Catholic Medical Center, Darby, PA 19023, USA.
Pranav PatelDepartment of Gastroenterology and Hepatology, Geisinger Health, Danville, PA 17822, USA.
Yash ShahDepartment of Medicine, Trinity Health Oakland/Wayne State University, Pontiac, MI 48341, USA.
Umar HayatDepartment of Medicine, Geisinger Health, Wikes Barre, PA 18765, USA.
Dushyant Singh DahiyaDepartment of Gastroenterology, Hepatology and Motility, University of Kansas School of Medicine, Kansas City, KS 66103, USA.
Dhruvil RadadiyaDepartment of Gastroenterology and Hepatology, Cedar Sinai Medical Center, Los Angeles, CA 90048, USA.
Hareesha Rishab BharadwajFaculty of Biology Medicine and Health, The University of Manchester, UK.
Doantrang DuDepartment of Medicine, Rutgers School of Medicine/Monmouth Medical Center, Long Branch, NJ 07740, USA.
Ben TerranyDepartment of Gastroenterology and Hepatology, Monmouth Medical Center, NJ 07740, USA.
Dharmesh KaswalaDepartment of Gastroenterology and Hepatology, Monmouth Medical Center, NJ 07740, USA.
Bradley ConferDepartment of Gastroenterology and Hepatology, Geisinger Health, Danville, PA 17822, USA.
Harshit S KharaDepartment of Gastroenterology and Hepatology, Geisinger Health, Danville, PA 17822, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Acute cholangitis (AC) is a serious condition caused by partial or complete obstruction of the common bile duct (CBD), leading to biliary tract infection. We aimed to evaluate whether teaching hospitals with trainees and non-teaching hospitals impact the outcome of AC in the United States. Methods: This study utilized the National Inpatient Sample database to analyze adult hospitalizations (> 18 years old) with a primary diagnosis of AC in the USA from 2016 to 2020. A multivariate logistic regression along with Chi-square and Results: This study included a total of 30,300 patients, out of whom 23,535 (about 78%) were managed in teaching hospitals and 6,765 (about 22%) were managed in non-teaching hospitals. Primary outcomes showed a significant increase in mortality for patients managed in teaching hospitals (2.77% vs. 2.08%, P = 0.01) in comparison to non-teaching hospitals, hospital LOS was slightly higher in teaching hospitals (5 days (interquartile range (IQR): 3 - 6) vs. 4 days (IQR: 3 - 8)) and so did hospital cost ($15,259 vs. $14,506) in comparison to non-teaching hospitals. Secondary outcomes showed that patients in teaching hospitals had higher incidence of septic shock (16.06% vs. 12.53%, P < 0.0001), intensive care unit (ICU) admissions (6.61% vs. 5.07%, P = 0.0002), and intubation (5.30% vs. 3.46%, P < 0.0001) in comparison to non-teaching hospitals. Conclusion: Our study found higher mortality rates for AC patients in teaching hospitals compared to non-teaching hospitals. Teaching hospitals also had higher rates of septic shock, ICU admission, and intubation, with no difference in endoscopic retrograde cholangiopancreatography (ERCP) use. These differences could be due to several factors, such as greater resident and fellow autonomy in teaching hospitals and a potentially more proactive approach by physicians in non-teaching hospitals. Additionally, teaching hospitals often manage more complex, higher-acuity cases, which could contribute to worse outcomes.

Indexed as

Acute cholangitisHospital chargesHospital length of stayHospital mortalityNational Inpatient Sample databaseOutcomesTeaching hospitals

Identifiers

PMID40503189
PMCPMC12151124

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.