Evidence map›Paper›PMID 40503188›Full record

ArticleGastroenterology research2025

Secondary Hyperparathyroidism in Primary Intestinal Lymphangiectasia: A Report of Four Cases.

Dong Xue Zhang, Kun Hao, Li Zhang, Wen Bin Shen, Tao Jiang

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Gastroenterology research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dong Xue ZhangDepartment of Endocrinology, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.
Kun HaoDepartment of Lymphatic Surgery, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.
Li ZhangDepartment of Nuclear Medicine, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.
Wen Bin ShenDepartment of Lymphatic Surgery, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.
Tao JiangDepartment of Lymphatic Surgery, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary intestinal lymphangiectasia (PIL) is a rare disease characterized by the loss of lymphatic fluid in the intestinal lumen and is a known cause of protein-losing enteropathy (PLE). Although uncommon, few cases of secondary hyperparathyroidism (SHPT) have been reported in patients with PIL. This study summarizes the characteristics of four cases diagnosed with PIL. Notably, all cases were confirmed to have hyperparathyroidism secondary to vitamin D deficiency and hypocalcemia. Recurrent diarrhea and limb convulsions were also observed in all patients, with one patient diagnosed with osteoporosis. Simultaneously, hypomagnesemia was detected in three cases. Treatment with vitamin D and calcium supplements relieved symptoms, elevated serum calcium levels, and decreased parathyroid hormone (PTH) levels. In patients with PIL, evaluation of 25-hydroxyvitamin D, calcium, and PTH levels is crucial. Bone diseases should be considered in patients with SHPT, and appropriate vitamin D3 and calcium supplementation is highly recommended.

Indexed as

CalciumMagnesiumPrimary intestinal lymphangiectasiaSecondary hyperparathyroidismVitamin D

Identifiers

PMID40503188
PMCPMC12151104

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.