Observational studyClinical interventions in aging2025
Effects of HALP Score, C-Reactive Protein/Albumin Ratio, and Platelet/Lymphocyte Ratio on Predicting Mortality in Geriatric Patients in the Respiratory Intensive Care Unit.
Observational study in Clinical interventions in aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Nutritional-inflammatory indices optimize the diagnostic performance of FIB-4 for advanced fibrosis/cirrhosis in patients with benign liver disease.Annals of medicine · 2026Article
- The C-Reactive Protein/Albumin Ratio Predicts In-Hospital Mortality Across Age Groups.Nutrients · 2026Article
- Neutrophil-to-Lymphocyte Ratio, Systemic Immune-Inflammation Index, and HALP Score as Predictors of Mortality in Acute Respiratory Distress Syndrome.Journal of clinical medicine · 2026Article
- Early Peri-Admission Lactate-to-Albumin (LAR), C-Reactive Protein-to-Albumin (CAR), and Procalcitonin-to-Albumin (PAR) Ratios and ICU Mortality in a Tertiary Cardiac ICU.Journal of clinical medicine · 2026Article
- A Machine Learning Model Integrating Systemic Immune-Inflammation Index for Predicting 28-Day Mortality in Geriatric Sepsis Secondary to Community-Acquired Bacterial Pneumonia.Clinical interventions in aging · 2026Article
- Strengthening Health Systems to Overcome Respiratory Infectious Diseases in Indonesia: A Comprehensive Review.Risk management and healthcare policy · 2026Review
- Admission lactate and short-term mortality in the geriatric ICU: comparison with established severity scores.Aging clinical and experimental research · 2025Article
- Association between C-reactive protein/albumin ratio and mortality in older Japanese patients with post-stroke dysphagia.Frontiers in neurology · 2025Article
- Interpretable Machine Learning Model for Early Mortality Prediction in Septic Patients Using Routine Post-Diagnosis Clinical Data: A Multicenter Study.Journal of inflammation research · 2025Article
- Development and Validation of a Nomogram for Predicting Sepsis-Associated Acute Respiratory Distress Syndrome.International journal of general medicine · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aim: This study aims to evaluate the effects of the hemoglobin, albumin, lymphocyte, and platelet (HALP) score, C-reactive protein/albumin ratio (CAR), and platelet/lymphocyte ratio (PLR) on predicting mortality in geriatric patients admitted to the respiratory intensive care unit (ICU). Materials and Methods: In this retrospective observational cohort study, data of patients followed up in the respiratory ICU between 01.07.2021 and 31.12.2023 were evaluated. Age, gender, HALP score, hemoglobin, albumin, lymphocyte, platelet, and C-reactive protein (CRP) levels, along with PLR, CAR, and patient prognosis (exitus/discharge), were recorded from patient files and the hospital data processing system. Results: The study included 405 patients (140 women and 265 men) over 65 years of age. In multivariate analysis, higher PLR and CAR values were associated with a higher mortality rate, whereas patients with a higher HALP score had a lower mortality rate (p<0.001). In the ROC analysis, a statistically significant cut-off value was found for the HALP score in predicting mortality (p<0.001). HALP score ≤ 9.94 indicates mortality, with a sensitivity of 67.25%, specificity of 53%, PPV (positive predictive value) of 64.98%, and NPV (negative predictive value) of 55%. CAR value ≥ 30.13 indicates mortality, with a sensitivity of 69.87%, specificity of 61.36%, PPV of 70.18% and NPV of 61.02%. There was no statistically significant cut-off value for PLR in predicting mortality (p=0.076). Conclusion: We found that the HALP score, PLR value, and CAR value are important scores that may be useful in determining mortality and treatment modality in geriatric patients treated in the ICU.
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