Evidence map›Paper›PMID 40503024›Full record

ArticleArXiv2025

PixCell: A generative foundation model for digital histopathology images.

Srikar Yellapragada, Alexandros Graikos, Zilinghan Li, Kostas Triaridis, Varun Belagali, Saarthak Kapse, Tarak Nath Nandi, Ravi K Madduri, Prateek Prasanna, Tahsin Kurc and 3 more

Abstract readPreprint
In one paragraph

Article in ArXiv, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Srikar YellapragadaStony Brook University.
Alexandros GraikosStony Brook University.
Zilinghan LiArgonne National Laboratory.
Kostas TriaridisStony Brook University.
Varun BelagaliStony Brook University.
Saarthak KapseStony Brook University.
Tarak Nath NandiArgonne National Laboratory.
Ravi K MadduriArgonne National Laboratory.
Prateek PrasannaStony Brook University.
Tahsin KurcStony Brook University.
Rajarsi R GuptaStony Brook University.
Joel SaltzStony Brook University.
Dimitris SamarasStony Brook University.

Funding

TCIA Sustainment and Scalability - Platforms for Quantitative Imaging Informatics in Precision MedicineU24CA215109 · NCI · UNIV OF ARKANSAS FOR MED SCIS · PI BANERJEE, IMON, PRIOR, FRED WILLIAM · 2017 to 2021
$8.5M
Tools to Analyze Morphology and Spatially Mapped Molecular DataU24CA180924 · NCI · STATE UNIVERSITY NEW YORK STONY BROOK · PI SALTZ, JOEL H. · 2014 to 2019
$3.6M
Methods and Tools for Integrating Pathomics Data into Cancer RegistriesUH3CA225021 · NCI · STATE UNIVERSITY NEW YORK STONY BROOK · PI CLIFFORD, GARI DAVID, DURBIN, ERIC B. · 2020 to 2022
$1.9M
IMAT-ITCR Collaboration: Combining FIBI and topological data analysis: Synergistic approaches for tumor structural microenvironment explorationR21CA258493 · NCI · STATE UNIVERSITY NEW YORK STONY BROOK · PI CHEN, CHAO, PRASANNA, PRATEEK · 2022 to 2023
$467k
NCI NIH HHS R21 CA258493NCI NIH HHS U24 CA180924NCI NIH HHS U24 CA215109NCI NIH HHS UH3 CA225021
6 · The paper itself

Abstract

The digitization of histology slides has revolutionized pathology, providing massive datasets for cancer diagnosis and research. Contrastive self-supervised and vision-language models have been shown to effectively mine large pathology datasets to learn discriminative representations. On the other hand, generative models, capable of synthesizing realistic and diverse images, present a compelling solution to address unique problems in pathology that involve synthesizing images; overcoming annotated data scarcity, enabling privacy-preserving data sharing, and performing inherently generative tasks, such as virtual staining. We introduce

Identifiers

PMID40503024
PMCPMC12154918

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.