Evidence map›Paper›PMID 40503014›Full record

ArticleArXiv2025

Learning to cluster neuronal function.

Nina S Nellen, Polina Turishcheva, Michaela Vystrčilová, Shashwat Sridhar, Tim Gollisch, Andreas S Tolias, Alexander S Ecker

Abstract readPreprint
In one paragraph

Article in ArXiv, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nina S NellenInstitute of Computer Science and Campus Institute Data Science, University Göttingen, Germany.
Polina TurishchevaInstitute of Computer Science and Campus Institute Data Science, University Göttingen, Germany.
Michaela VystrčilováInstitute of Computer Science and Campus Institute Data Science, University Göttingen, Germany.
Shashwat SridharUniversity Medical Center Göttingen, Department of Ophthalmology, Göttingen, Germany.
Tim GollischUniversity Medical Center Göttingen, Department of Ophthalmology, Göttingen, Germany.
Andreas S ToliasDepartment of Ophthalmology, Byers Eye Institute, Stanford University School of Medicine, Stanford, CA, US.
Alexander S EckerInstitute of Computer Science and Campus Institute Data Science, University Göttingen, Germany.

Funding

Generation of novel cell type specific mouse genetic toolsU19MH114830 · NIMH · ALLEN INSTITUTE · PI ZENG, HONGKUI · 2017 to 2021
$64.7M
VISION RESEARCH CENTERP30EY002520 · NEI · BAYLOR COLLEGE OF MEDICINE · PI Samuel M Wu · 1985 to 2026
$14.8M
Probabilistic coding in cortical populationsR01EY026927 · NEI · BAYLOR COLLEGE OF MEDICINE · PI MA, WEI JI, TOLIAS, ANDREAS · 2017 to 2021
$1.9M
NEI NIH HHS P30 EY002520NEI NIH HHS R01 EY026927NIMH NIH HHS U19 MH114830
6 · The paper itself

Abstract

Deep neural networks trained to predict neural activity from visual input and behaviour have shown great potential to serve as digital twins of the visual cortex. Per-neuron embeddings derived from these models could potentially be used to map the functional landscape or identify cell types. However, state-of-the-art predictive models of mouse V1 do not generate functional embeddings that exhibit clear clustering patterns which would correspond to cell types. This raises the question whether the lack of clustered structure is due to limitations of current models or a true feature of the functional organization of mouse V1. In this work, we introduce DECEMber - Deep Embedding Clustering via Expectation Maximization-based refinement - an explicit inductive bias into predictive models that enhances clustering by adding an auxiliary

Identifiers

PMID40503014
PMCPMC12155019

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.