Evidence map›Paper›PMID 40502849›Full record

ArticleEpilepsy & behavior reports2025

Mental health intervention for a child with developmental and/or epileptic encephalopathy with spike-wave activation in sleep (D/EE-SWAS).

C Reilly, Roz Shafran, Helen Cross, Millie Wagstaff, Bhavna Sidhpara, J Idowu, C Meades, S D Bennett

Abstract readCase Reports
In one paragraph

Article in Epilepsy & behavior reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

C ReillyResearch Department, Young Epilepsy, Lingfield, Surrey RH7 6PW, UK.
Roz ShafranUCL Great Ormond Street Institute of Child Health (ICH), 30 Guilford Street London WC1N 1EH UK.
Helen CrossResearch Department, Young Epilepsy, Lingfield, Surrey RH7 6PW, UK.
Millie WagstaffUCL Great Ormond Street Institute of Child Health (ICH), 30 Guilford Street London WC1N 1EH UK.
Bhavna SidhparaResearch Department, Young Epilepsy, Lingfield, Surrey RH7 6PW, UK.
J IdowuResearch Department, Young Epilepsy, Lingfield, Surrey RH7 6PW, UK.
C MeadesResearch Department, Young Epilepsy, Lingfield, Surrey RH7 6PW, UK.
S D BennettUCL Great Ormond Street Institute of Child Health (ICH), 30 Guilford Street London WC1N 1EH UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Children with Developmental and Epileptic Encephalopathies experience neurodevelopmental problems from both the epileptic activity and the underlying cause of the condition. Children with Developmental and/or Epileptic Encephalopathy with spike-wave activation in sleep (D/EE-SWAS) experience cognitive and behavioral regression/stagnation that occurs in tandem with marked spike-wave activation in sleep (SWAS). Children with epilepsy often have co-occurring mental health problems that are often not recognized or supported. There is increasing evidence these co-occurring mental health problems can be treated with psychological interventions. The mental health and cognitive difficulties that accompany SWAS have a significant impact on child and family quality of life. There is limited data on the treatment of mental health difficulties for children with D/EE-SWAS. We describe the use of the Mental Health Intervention in Children with Epilepsy (MICE) in a child with D/EE-SWAS who had experienced significant cognitive regression and behavioral difficulties. The intervention was delivered with the child's parents via video and consisted of 19 sessions delivered by an assistant psychologist. The focus of the intervention was reducing behaviours of concern via evidence-based behavioural parenting strategies. The intervention resulted in clear progress towards parental chosen goals (Goal Based Outcomes) and a reduction of symptoms on validated measures of behavior. Qualitative feedback via parental interview was that the intervention was very useful, giving the parents everyday strategies that they could effectively employ with the child in the home environment. This case demonstrates that a mental health intervention based on behavioural parenting strategies can be useful for children with D/EE-SWAS.

Indexed as

Developmental and epileptic encephalopathyEpilpesyMental health

Identifiers

PMID40502849
PMCPMC12152331

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.