In one paragraphArticle in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
15 authors.
Cameron DurfeeDepartment of Biochemistry and Structural Biology, University of Texas Health San Antonio, San Antonio, Texas, USA, 78229.ORCID 0000-0002-8130-4270 Erik N BergstromDepartment of Cellular and Molecular Medicine, University of California San Diego, La Jolla, California, USA, 92093.
Marcos Díaz-GayDepartment of Cellular and Molecular Medicine, University of California San Diego, La Jolla, California, USA, 92093.ORCID 0000-0003-0658-0467 Yufan ZhouDepartment of Biochemistry and Structural Biology, University of Texas Health San Antonio, San Antonio, Texas, USA, 78229.ORCID 0000-0002-8385-433X Nuri Alpay TemizInstitute for Health Informatics, University of Minnesota, Minneapolis, Minnesota, USA, 55455.ORCID 0000-0003-1416-3639 Mahmoud A IbrahimDepartment of Biochemistry and Structural Biology, University of Texas Health San Antonio, San Antonio, Texas, USA, 78229.
Shuvro P NandiDepartment of Cellular and Molecular Medicine, University of California San Diego, La Jolla, California, USA, 92093.ORCID 0000-0003-4855-4697 Yaxi WangDepartment of Biochemistry and Structural Biology, University of Texas Health San Antonio, San Antonio, Texas, USA, 78229.ORCID 0009-0000-2401-4712 Xingyu LiuDepartment of Biochemistry and Structural Biology, University of Texas Health San Antonio, San Antonio, Texas, USA, 78229.
Christopher D SteeleDepartment of Cellular and Molecular Medicine, University of California San Diego, La Jolla, California, USA, 92093.
Joshua ProehlDepartment of Biochemistry and Structural Biology, University of Texas Health San Antonio, San Antonio, Texas, USA, 78229.
Prokopios P ArgyrisDivision of Oral and Maxillofacial Pathology, College of Dentistry, Ohio State University, Columbus, Ohio, USA, 43210.
Ludmil B AlexandrovDepartment of Cellular and Molecular Medicine, University of California San Diego, La Jolla, California, USA, 92093.ORCID 0000-0003-3596-4515 Reuben S HarrisDepartment of Biochemistry and Structural Biology, University of Texas Health San Antonio, San Antonio, Texas, USA, 78229.ORCID 0000-0002-9034-9112 Funding
TISSUE CULTURE---COREP30CA054174 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Lei Zheng · 1991 to 2026
$59.1MTargeting Polθ to Overcome PARP Inhibitor Resistance in Homologous Recombination Deficient Breast CancerP50CA247749 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI Sarat Chandarlapaty, Simon N. Powell · 2020 to 2026
$16.3MPROJECT 3 – BIOLOGY OF DNA DEAMINASES IN CANCERP01CA234228 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Michael Allen Carpenter · 2019 to 2026
$14.5MRole of hypernutrition and metabolic stress in non-alcoholic steatohepatitis (NASH) driven hepatocellular carcinoma (HCC)P01CA281819 · NCI · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI Michael Karin · 2024 to 2026
$9.2MDetecting Mutational Signatures of Environmental Mutagens in Heathy Individuals for Personalized Cancer PreventionR01ES032547 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ALEXANDROV, LUDMIL B · 2021 to 2025
$3.4MMapping immuno-genomic drivers of the head and neck precancer invasive-disease transitionU01CA290479 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Ludmil B Alexandrov, Jorge Silvio Gutkind · 2023 to 2026
$3.1MComprehensive identification of germline-somatic interactionsR01CA269919 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Ludmil B Alexandrov, Hannah Kathryn Carter · 2022 to 2026
$2.2MIllumina NovaSeq 6000 Sequencing SystemS10OD030311 · OD · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI LAI, ZHAO · 2021 to 2021
$600kNCI NIH HHS P01 CA234228NCI NIH HHS P01 CA281819NCI NIH HHS P30 CA054174NCI NIH HHS P50 CA247749NCI NIH HHS R01 CA269919NCI NIH HHS U01 CA290479NIEHS NIH HHS R01 ES032547NIH HHS S10 OD030311
6 · The paper itselfAbstract
Mutations in somatic cells are inflicted by both extrinsic and intrinsic sources and contribute over time to cancer. Tobacco smoke contains chemical carcinogens that have been causatively implicated with cancers of the lung and head & neck
Indexed as
APOBEC mutagenesisbulky DNA adductscancer development and progressionnucleotide excision repairtobacco carcinogens
Identifiers
PMID40502742
PMCPMC12155223
What OpenQuestion holds
Textmetadata
LicenceCC BY
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