Evidence map›Paper›PMID 40502680›Full record

ArticleJournal of hepatocellular carcinoma2025

Genetic Variants of

Rongbin Gong, Moqin Qiu, Yingchun Liu, Ji Cao, Zihan Zhou, Qiuling Lin, Yanji Jiang, Xiumei Liang, Yuying Wei, Qiuping Wen and 7 more

Abstract read
In one paragraph

Article in Journal of hepatocellular carcinoma, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Rongbin Gong *Department of Experimental Research, Guangxi Medical University Cancer Hospital, Nanning, People's Republic of China.
Moqin Qiu *Department of Respiratory Oncology, Guangxi Medical University Cancer Hospital, Nanning, People's Republic of China.
Yingchun LiuDepartment of Experimental Research, Guangxi Medical University Cancer Hospital, Nanning, People's Republic of China.
Ji CaoDepartment of Cancer Prevention and Control, Guangxi Medical University Cancer Hospital, Nanning, People's Republic of China.
Zihan ZhouDepartment of Cancer Prevention and Control, Guangxi Medical University Cancer Hospital, Nanning, People's Republic of China.ORCID 0000-0003-1444-4713
Qiuling LinDepartment of Clinical Research, Guangxi Medical University Cancer Hospital, Nanning, People's Republic of China.
Yanji JiangDepartment of Scientific Research, Guangxi Medical University Cancer Hospital, Nanning, People's Republic of China.
Xiumei LiangDepartment of Disease Process Management, Guangxi Medical University Cancer Hospital, Nanning, People's Republic of China.
Yuying WeiDepartment of Experimental Research, Guangxi Medical University Cancer Hospital, Nanning, People's Republic of China.
Qiuping WenDepartment of Experimental Research, Guangxi Medical University Cancer Hospital, Nanning, People's Republic of China.
Peiqin ChenDepartment of Experimental Research, Guangxi Medical University Cancer Hospital, Nanning, People's Republic of China.
Xiaoxia WeiDepartment of Clinical Research, Guangxi Medical University Cancer Hospital, Nanning, People's Republic of China.
Junjie WeiDepartment of Experimental Research, Guangxi Medical University Cancer Hospital, Nanning, People's Republic of China.
Shicheng ZhanDepartment of Experimental Research, Guangxi Medical University Cancer Hospital, Nanning, People's Republic of China.ORCID 0009-0007-2266-3939
Ruoxin ZhangSchool of Public Health, Key Laboratory of Public Health Safety, Ministry of Education, Fudan University, Shanghai, People's Republic of China.
Dong YeDepartment of Integrated Medicine, Guangxi Medical University Cancer Hospital, Nanning, People's Republic of China.
Hongping YuDepartment of Experimental Research, Guangxi Medical University Cancer Hospital, Nanning, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Glycolysis is a group of metabolic processes that may alter tumor microenvironment to have effects on the growth and proliferation of tumor cells, including liver cancer. However, the effect of genetic variants in glycolysis pathway genes in survival of patients with hepatitis B virus-related hepatocellular carcinoma (HBV-HCC) remains unclear. Methods: We employed multivariable Cox proportional hazards regression analyses to estimate associations between genetic variants in 240 glycolysis pathway genes and overall survival (OS) of 866 patients with HBV-HCC, and we also used false positive report probability for multiple testing corrections. Results: We found that Discussion: Our findings suggested that genetic variants in glycolysis pathway genes may serve as novel prognostic markers for survival of patients with HBV-HCC, especially

Indexed as

glycolysishepatitis B virushepatocellular carcinomaover survivalsingle nucleotide polymorphism

Identifiers

PMID40502680
PMCPMC12155380

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.