Evidence map›Paper›PMID 40502517›Full record

ArticleWorld journal of gastrointestinal surgery2025

Efficacy of reinforcing sutures in preventing anastomotic leakage after surgery for rectal cancer: A systematic review and metaanalysis.

Zi-Xuan Zhuang, Yang Zhang, Xu-Yang Yang, Zi-Qiang Wang, Xiang-Bing Deng, Ming-Ming Zhang

Abstract read
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Article in World journal of gastrointestinal surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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0cells of the map it votes in
3citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Zi-Xuan ZhuangColorectal Cancer Center, Department of General Surgery, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, China.
Yang ZhangColorectal Cancer Center, Department of General Surgery, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, China.
Xu-Yang YangColorectal Cancer Center, Department of General Surgery, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, China.
Zi-Qiang WangColorectal Cancer Center, Department of General Surgery, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, China.
Xiang-Bing DengColorectal Cancer Center, Department of General Surgery, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, China.
Ming-Ming ZhangColorectal Cancer Center, Department of General Surgery, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, China. zhangmm@scu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnastomotic leakage (AL) is a challenging complication following rectal cancer surgery, often leading to increased morbidity and healthcare costs. The use of reinforcement sutures is expected to reduce the rate of AL, their preventive effects are controversial.

aimTo determine the efficacy of reinforcing sutures in preventing AL in rectal cancer.

methodsA systematic search of major medical databases was conducted to identify studies up to June 2024. Intraoperative and postoperative outcomes were assessed; the primary outcome assessed was the incidence of AL. Pooled odds ratios (ORs) and mean differences (MDs) with a 95% confidence interval (CI) were calculated using fixed-effect or random-effect models under heterogeneity.

resultsThis meta-analysis incorporated 20 studies involving 3726 patients. Pooled results demonstrated a statistically significant reduction AL incidence in the reinforced suture group (OR: 0.26, 95%CI: 0.19-0.35,

conclusionThe results substantiate the clinical value of anastomotic reinforcement sutures in reducing AL incidence post-rectal cancer surgery. Nevertheless, these conclusions warrant verification through additional high-quality randomized controlled trials.

Indexed as

Anastomotic leakageMeta-analysisRectal cancerReinforcing sutureSystematic review

Identifiers

PMID40502517
PMCPMC12149912

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