ArticleWorld journal of gastrointestinal surgery2025
Nutritional and inflammatory indicators differ among patients with colorectal cancer with distinct microsatellite stability statuses.
Article in World journal of gastrointestinal surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Construction and Validation of Multi-Omics Predictive Models for Colorectal Cancer Using Machine-Learning Approaches.Pharmacogenomics and personalized medicine · 2026Article
- Microsatellite instability and its impact on nutritional and inflammatory profiles in colorectal cancer.World journal of gastrointestinal surgery · 2025Article
- Integrating nutritional and inflammatory biomarkers in colorectal cancer management: Implications of microsatellite instability status.World journal of gastrointestinal surgery · 2025Article
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Authors and funding
7 authors.
Funding
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Abstract
backgroundNutritional and inflammatory indicators are crucial in assessing the nutritional health and immune function of patients with cancer, which are factors closely associated with the diagnosis and treatment of colorectal cancer (CRC).
aimTo explore the relationship between nutritional and inflammatory indicators and microsatellite stability (MSS) status in CRC.
methodsThe clinical data of 56 patients who underwent surgical treatment for CRC were collected. Furthermore, the expressions of nutritional (levels of serum albumin, triglycerides, serum cholesterol, and body mass index) and inflammatory response indicators (absolute neutrophil count, absolute lymphocyte count, absolute monocyte count, neutrophil-to-lymphocyte ratio, and lymphocyte-to-monocyte ratio) as well as their correlation with microsatellite instability (MSI) status were investigated in patients with CRC.
resultsCompared to the patients with MSS tumors, those with MSI tumors demonstrated significantly lower levels of two nutritional indicators, namely serum albumin and body mass index (
conclusionCertain nutritional and inflammatory indicators exhibit significant differences among patients with MSI and MSS CRC, highlighting their potential role in the clinical treatment and health management of this specific population.
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