Evidence map›Paper›PMID 40502501›Full record

ReviewWorld journal of gastrointestinal surgery2025

Association between hematological disorders and gallbladder stones: A review of current evidence.

Zhi-Jie Qu, Yu-Ning Wang, Ya-Hui Liu, Rui-Heng Duan

Abstract readReview
In one paragraph

Review in World journal of gastrointestinal surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zhi-Jie QuDepartment of Nephrology, Second Hospital of Jilin University, Changchun 130022, Jilin Province, China.
Yu-Ning WangDepartment of Breast Surgery, China-Japan Union Hospital of Jilin University, Changchun 130022, Jilin Province, China.
Ya-Hui LiuDepartment of Hepatobiliary and Pancreatic Surgery, General Surgery Center, The First Hospital of Jilin University, Changchun 130021, Jilin Province, China. yahui@jlu.edu.cn.
Rui-Heng DuanDepartment of Hepatobiliary-Pancreatic Surgery, China-Japan Union Hospital of Jilin University, Changchun 130022, Jilin Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gallbladder stones, a prevalent biliary tract disease, have multifactorial etiologies including metabolic, genetic, and environmental factors. Emerging evidence suggests that hematological disorders, particularly those involving hemolysis or impaired erythropoiesis, may play a significant role in the formation of gallbladder stones, predominantly pigment stones. This review explores the pathophysiological mechanisms linking hematological disorders, such as hemolytic anemias, myeloproliferative disorders, and hematological malignancies, with gallbladder stone development. We also examine the influence of treatments for hematological conditions, such as blood transfusions and chemotherapy, on gallstone risk. Additionally, this article discusses the clinical implications of gallbladder stones in patients with hematological disorders, including diagnostic challenges, management strategies, and surgical considerations. By providing a comprehensive overview of current knowledge, this review aims to highlight the need for further research into the interplay between hematological disorders and gallbladder stones, potentially improving preventive and therapeutic strategies in these patient populations.

Indexed as

Bilirubin metabolismChronic hemolysisGallbladder stonesGenetic factorsHematological disorders

Identifiers

PMID40502501
PMCPMC12149951

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.