Evidence map›Paper›PMID 40502394›Full record

ArticleFrontiers in veterinary science2025

Molecular mechanisms underlying cashmere quality differences between Jiangnan cashmere goats and Changthangi pashmina goats.

Gao Gong, Shijie Bi, Xin Liang, Yu Ao, Feng Xu, Yiming Sulaiman

Abstract read
In one paragraph

Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gao GongCollege of Animal Science, Xinjiang Agricultural University, Urumqi, China.
Shijie BiCollege of Food Science and Pharmacy, Xinjiang Agricultural University, Urumqi, China.
Xin LiangCollege of Animal Science, Xinjiang Agricultural University, Urumqi, China.
Yu AoCollege of Animal Science, Xinjiang Agricultural University, Urumqi, China.
Feng XuCollege of Animal Science, Xinjiang Agricultural University, Urumqi, China.
Yiming SulaimanCollege of Animal Science, Xinjiang Agricultural University, Urumqi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cashmere goats are excellent livestock breeds known for producing high-quality cashmere fibers from secondary hair follicles. In this study, we aimed to explore the key RNA molecules responsible for the differences in cashmere quality between Jiangnan cashmere goats (JNCG) and Changthangi pashmina goats (CPG). Skin transcriptomic data from the anagen, catagen, and telogen stages of hair follicle growth were retrieved from the SRA database for both JNCG and CPG. Bioinformatics analyses were conducted to identify key molecular differences underlying the variation in cashmere fiber quality. The results showed that there were 4,942 differentially expressed genes (DEGs) between JNCG and CPG through differential analysis, and the DEGs were mainly enriched in PI3K-Akt signaling pathway, Thermogenesis, ECM-receptor interaction in KEGG through functional enrichment analysis, and GO entries were mainly enriched in keratin filament, intermediate filament, keratinization. Twenty-four key candidate genes including

Indexed as

cashmere goatsKRTsPI3K-Akt signaling pathwayskin transcriptomethermogenesis

Identifiers

PMID40502394
PMCPMC12153449

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.