ArticlebioRxiv : the preprint server for biology2025
Co-release of opposing signaling molecules controls the escalation and release of aggression.
Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
12 authors.
Funding
Abstract
Neuropeptides exert broad effects across the brain to influence behavior. However, the mechanism by which the brain uses neuropeptide signaling to exert top-down control over complex behavioral responses remains poorly understood. Prolonged social isolation induces a distinct internal state that results in sweeping changes to behavior, including increased aggression. Here, we find that isolation-induced aggression activates Tachykinin-2 expressing (Tac2
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.