Evidence map›Paper›PMID 40502176›Full record

ArticlebioRxiv : the preprint server for biology2025

Unbiased profiling of multipotency landscapes reveals spatial modulators of clonal fate biases.

Alek G Erickson, Sergey Isaev, Artem Artemov, Jingyan He, Bettina Semsch, Aliia Murtazina, Jia Sun, Katrin Mangold, Anthi Chalou, Jonas Frisen and 4 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Alek G EricksonDepartment of Physiology and Pharmacology, Karolinska Institutet; 17177 Stockholm, Sweden.ORCID 0000-0001-7110-9386
Sergey IsaevDepartment of Neuroimmunology, Center for Brain Research, Medical University of Vienna; 1090 Vienna, Austria.ORCID 0000-0002-0404-9261
Artem ArtemovDepartment of Neuroimmunology, Center for Brain Research, Medical University of Vienna; 1090 Vienna, Austria.
Jingyan HeDepartment of Cell and Molecular Biology, Karolinska Institutet; 17177 Stockholm, Sweden.ORCID 0000-0002-7405-5800
Bettina SemschDepartment of Cell and Molecular Biology, Karolinska Institutet; 17177 Stockholm, Sweden.
Aliia MurtazinaDepartment of Physiology and Pharmacology, Karolinska Institutet; 17177 Stockholm, Sweden.ORCID 0000-0003-1630-1855
Jia SunDepartment of Comparative Medicine, Karolinska Institutet; 17177 Stockholm, Sweden.
Katrin MangoldDepartment of Cell and Molecular Biology, Karolinska Institutet; 17177 Stockholm, Sweden.ORCID 0000-0002-0656-462X
Anthi ChalouDepartment of Physiology and Pharmacology, Karolinska Institutet; 17177 Stockholm, Sweden.
Jonas FrisenDepartment of Cell and Molecular Biology, Karolinska Institutet; 17177 Stockholm, Sweden.ORCID 0000-0001-5819-458X
Michael RatzDepartment of Cell and Molecular Biology, Karolinska Institutet; 17177 Stockholm, Sweden.ORCID 0000-0002-9795-8033
Emma AnderssonDepartment of Cell and Molecular Biology, Karolinska Institutet; 17177 Stockholm, Sweden.ORCID 0000-0002-8608-625X
Peter V KharchenkoSan Diego Institute of Science, Altos Labs; San Diego, CA, USA.ORCID 0000-0002-6036-5875
Igor AdameykoDepartment of Physiology and Pharmacology, Karolinska Institutet; 17177 Stockholm, Sweden.ORCID 0000-0001-5471-0356

Funding

Signaling mechanisms underlying neural crest cell fate decisionsF32DE029662 · NIDCR · KAROLINSKA INSTITUTE · PI ERICKSON, ALEK G · 2021 to 2023
$219k
NIDCR NIH HHS F32 DE029662
6 · The paper itself

Abstract

Embryogenesis is commonly viewed through a tree model of cell differentiation, which fails to capture the spatiotemporal modulation of cell multipotency underlying morphogenesis. In this study we profile the multipotency landscape of the embryo, using

Identifiers

PMID40502176
PMCPMC12157653

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.