Evidence map›Paper›PMID 40502169›Full record

ArticlebioRxiv : the preprint server for biology2025

Platelet DKK1 promotes tolerogenic dendritic cells and non-healing responses in cutaneous leishmaniasis.

Olivia C Ihedioha, Anutr Sivakoses, Haley Q Marcarian, Malini Sajeev, Diane McMahon-Pratt, Alfred L M Bothwell

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Olivia C IhediohaDepartment of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, Nebraska, United States of America.ORCID 0000-0001-9079-0787
Anutr SivakosesDepartment of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, Nebraska, United States of America.ORCID 0000-0002-4321-4645
Haley Q MarcarianDepartment of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, Nebraska, United States of America.
Malini SajeevDepartment of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, Nebraska, United States of America.
Diane McMahon-PrattDepartment of Epidemiology of Infectious Diseases, Yale School of Public Health, New Haven, CT, United States of America.ORCID 0000-0003-0872-8779
Alfred L M BothwellDepartment of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, Nebraska, United States of America.ORCID 0000-0003-2487-2104

Funding

UNMC/EPPLEY CANCER CENTER SUPPORT GRANTP30CA036727 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI James Eudy · 1985 to 2026
$55.0M
Thrombocyte Regulation of Anti-Parasite ImmunityR01AI137060 · NIAID · YALE UNIVERSITY · PI BOTHWELL, ALFRED LM · 2019 to 2023
$2.0M
NCI NIH HHS P30 CA036727NIAID NIH HHS R01 AI137060
6 · The paper itself

Abstract

Dickkopf-1(DKK1) is a classical Wnt antagonist, which is released at the initiation of

Identifiers

PMID40502169
PMCPMC12154824

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.