Evidence map›Paper›PMID 40502106›Full record

ArticlebioRxiv : the preprint server for biology2025

Molecular mechanisms of immune evasion by host protein glycosylation of a bacterial immunogen used in nucleic acid vaccines.

M S Cinar, T M Adams, A Ozdilek, F Y Avci

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

M S CinarDepartment of Biochemistry, Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, 30322 USA.ORCID 0009-0006-5949-019X
T M AdamsDepartment of Biochemistry, Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, 30322 USA.ORCID 0000-0002-6661-1694
A OzdilekDepartment of Biochemistry, Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, 30322 USA.
F Y AvciDepartment of Biochemistry, Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, 30322 USA.ORCID 0000-0002-1902-7532

Funding

Molecular Mechanisms for Carbohydrate Presentation to CD4+ T cells by MHCII PathwayR01AI123383 · NIAID · UNIVERSITY OF GEORGIA · PI Fikri Y Avci · 2016 to 2026
$4.2M
Glycopeptide-specific helper T cells eliciting protective humoral immunity against HIV - ResubmissionR01AI152766 · NIAID · UNIVERSITY OF GEORGIA · PI Fikri Y Avci · 2021 to 2026
$2.6M
Pn3Pase as an Effective Enzyme Therapeutic for Streptococcus Pneumoniae type 3 InfectionR41AI157287 · NIAID · PNEUMOTACTIX, LLC · PI AVCI, FIKRI Y · 2021 to 2022
$599k
NIAID NIH HHS R01 AI123383NIAID NIH HHS R01 AI152766NIAID NIH HHS R41 AI157287
6 · The paper itself

Abstract

Nucleic acid vaccines, including mRNA platforms, represent a transformative approach by inducing adaptive immunity against

Indexed as

antigenicityglycomicsglycopeptidomicsimmunogenicitymammalian N-glycosylationmolecular dynamicsmRNA vaccinesMycobacterium tuberculosisnucleic acid vaccines

Identifiers

PMID40502106
PMCPMC12154765

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.