Evidence map›Paper›PMID 40502086›Full record

ArticlebioRxiv : the preprint server for biology2025

CryoEM structure of the

Saarang Kashyap, Xian Xia, Hui Wang, Michelle Shimogawa, Angela Agnew, Kent Hill, Z Hong Zhou

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Saarang KashyapDepartment of Microbiology, Immunology & Molecular Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0003-1732-4864
Xian XiaDepartment of Microbiology, Immunology & Molecular Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0001-9833-5017
Hui WangDepartment of Microbiology, Immunology & Molecular Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0002-9922-7170
Michelle ShimogawaDepartment of Microbiology, Immunology & Molecular Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Angela AgnewDepartment of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Kent HillDepartment of Microbiology, Immunology & Molecular Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Z Hong ZhouDepartment of Microbiology, Immunology & Molecular Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0002-8373-4717

Funding

Biochemical and Functional Analysis of TrypaninR01AI052348 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HILL, KENT L · 2002 to 2023
$7.4M
High-Resolution CryoEM Reconstruction of Large ComplexesR01GM071940 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ZHOU, Z HONG · 2006 to 2025
$5.0M
Trypanosome flagellum structure, assembly, and mechanismR01AI194637 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KENT L HILL · 2025 to 2026
$1.5M
Direct Detection Device for atomic resolution cryoEM of macromolecular complexesS10OD018111 · OD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ZHOU, Z HONG · 2014 to 2014
$598k
NIAID NIH HHS R01 AI052348NIAID NIH HHS R01 AI194637NIGMS NIH HHS R01 GM071940NIH HHS S10 OD018111
6 · The paper itself

Abstract

Axonemes are cylindrical bundles of microtubule filaments that typically follow a 9+n pattern (where

Indexed as

central apparatuscryoEMflagellumTrypanosoma brucei

Identifiers

PMID40502086
PMCPMC12154619

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.