Evidence map›Paper›PMID 40502082›Full record

ArticlebioRxiv : the preprint server for biology2025

Hierarchical diversification of instinctual behavior neurons by lineage, birth order, and sex.

Najia Elkahlah, Yunzhi Lin, Troy R Shirangi, E Josephine Clowney

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Najia ElkahlahCellular and Molecular Biology Program, University of Michigan Medical School, Ann Arbor, Michigan 48109.ORCID 0000-0002-9657-1777
Yunzhi LinDepartment of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109.
Troy R ShirangiDepartment of Biology, Villanova University, Villanova, PA 19085.ORCID 0000-0002-8205-9318
E Josephine ClowneyDepartment of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109.ORCID 0000-0002-9150-9464

Funding

CELLULAR AND MOLECULAR BIOLOGY AT MICHIGANT32GM007315 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PUTHENVEEDU, MANOJKUMAR A · 1985 to 2021
$12.8M
Cellular and Molecular Biology at MichiganT32GM145470 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI John Chadwick Brenner · 2022 to 2026
$4.1M
Generation and manipulation of combinatorial connectivity in olfactory perceptionR01DC018032 · NIDCD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Eleanor Josephine Clowney · 2020 to 2026
$2.7M
Intersecting roles for lineage and sex in the development of innate behavior circuitsF99NS139459 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ELKAHLAH, NAJIA · 2024 to 2025
$66k
NIDCD NIH HHS R01 DC018032NIGMS NIH HHS T32 GM007315NIGMS NIH HHS T32 GM145470NINDS NIH HHS F99 NS139459
6 · The paper itself

Abstract

Brain regions devoted to instinctual behaviors, including the vertebrate hypothalamus and arthropod cerebrum, contain bespoke neural circuits dedicated to perceptual and internal regulation of many behavioral states. These circuits are usually complex in structure and contain an extensive diversity of cell types. The regulatory mechanisms that pattern circuits for instinctual behaviors have been challenging to elucidate. Here, we developed methods in

Identifiers

PMID40502082
PMCPMC12157605

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.