Evidence map›Paper›PMID 40502043›Full record

ArticlebioRxiv : the preprint server for biology2025

Intrinsic Repair Capacity of Resident Tendon Cells is Dependent on Hole Size in an Ex Vivo Model of Laser-Induced Microdamage.

Anthony N Aggouras, Matthew T Lim, Jeroen Eyckmans, Brianne K Connizzo

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anthony N AggourasDepartment of Biomedical Engineering, Boston University, Boston, MA, 02215, United States.
Matthew T LimDepartment of Biomedical Engineering, Boston University, Boston, MA, 02215, United States.
Jeroen EyckmansDepartment of Biomedical Engineering, Boston University, Boston, MA, 02215, United States.
Brianne K ConnizzoDepartment of Biomedical Engineering, Boston University, Boston, MA, 02215, United States.

Funding

Innate and Hormone-Mediated Sex Differences in Extracellular Matrix RemodelingR35GM151127 · NIGMS · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI Brianne Kathryn Connizzo · 2023 to 2026
$1.6M
Development of In Vitro Compression-Induced Rotator Cuff Injury Model: Aging and Inflammation in Tendon DegenerationR00AG063896 · NIA · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI CONNIZZO, BRIANNE KATHRYN · 2021 to 2023
$830k
Development of a wound-on-chip model to study stromal-epithelial interactions during tissue repairR21EB028491 · NIBIB · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI EYCKMANS, JEROEN · 2020 to 2022
$660k
Advanced laser scanning confocal microscope for multiple usersS10OD024993 · OD · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI MERTZ, JEROME · 2018 to 2018
$448k
NIA NIH HHS R00 AG063896NIBIB NIH HHS R21 EB028491NIGMS NIH HHS R35 GM151127NIH HHS S10 OD024993
6 · The paper itself

Abstract

While it is generally accepted that tendon healing following widespread extracellular matrix trauma is limited, tenocytes are thought to have the capacity to repair small amounts of microdamage generated through activities of daily living. Despite this, few studies have directly studied the mechanisms governing this process. To address this, we developed a tunable

Indexed as

healingmatrix remodelingMicrodamagetendon explant

Identifiers

PMID40502043
PMCPMC12154869

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.