ArticlebioRxiv : the preprint server for biology2025
Obesity dysregulates feeding-evoked response dynamics in hypothalamic satiety neurons.
Marta Porniece, Jessica Baker, Charlotte D Ausfahl, Stephen X Zhang, Mark L Andermann
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
5 authors.
Marta PornieceDivision of Endocrinology, Diabetes and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 02115, Boston, MA, USA.ORCID 0000-0003-2330-5846 Jessica BakerDivision of Endocrinology, Diabetes and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 02115, Boston, MA, USA.
Charlotte D AusfahlDivision of Endocrinology, Diabetes and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 02115, Boston, MA, USA.
Stephen X ZhangDivision of Endocrinology, Diabetes and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 02115, Boston, MA, USA.
Mark L AndermannDivision of Endocrinology, Diabetes and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 02115, Boston, MA, USA.
Funding
Transgenic CoreP30DK046200 · NIDDK · TUFTS MEDICAL CENTER · PI LOWELL, BRADFORD B · 1992 to 2021
$25.0MNeuromodulatory mechanisms underlying vagus nerve stimulation therapy for Alzheimer's diseaseDP1AT010971 · NCCIH · BETH ISRAEL DEACONESS MEDICAL CENTER · PI ANDERMANN, MARK L · 2019 to 2023
$6.6MHigh-dimensional chemical targeting of multiple neuron types to regulate energy balanceDP1DK139958 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI Mark L Andermann · 2024 to 2026
$2.4MNeural Pathway Linking Nutritional State To Food-Cue Responses In Insular CortexR01DK109930 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI ANDERMANN, MARK L · 2016 to 2020
$2.2MCompeting effects of AgRP and POMC neurons on cAMP signaling in downstream neurons in vivoK99DK134853 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI ZHANG, XINGJIE · 2023 to 2024
$182kNCCIH NIH HHS DP1 AT010971NIDDK NIH HHS DP1 DK139958NIDDK NIH HHS K99 DK134853NIDDK NIH HHS P30 DK046200NIDDK NIH HHS R01 DK109930
6 · The paper itselfAbstract
Melanocortin-4 receptor-expressing neurons in the paraventricular nucleus of the hypothalamus (PVH
Identifiers
PMID40502019
PMCPMC12154894
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