Evidence map›Paper›PMID 40502011›Full record

ArticlebioRxiv : the preprint server for biology2025

Deciphering the combinatorial expression pattern and genetic regulatory mechanisms of Beats and Sides in the olfactory circuits of

Qichen Duan, Sumie Okuwa, Rachel Estrella, Chun Yeung, Yu-Chieh David Chen, Laura Quintana Rio, Khanh M Vien, Pelin C Volkan

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Qichen DuanDepartment of Biology, Duke University, Durham, NC 27708, USA.
Sumie OkuwaDepartment of Biology, Duke University, Durham, NC 27708, USA.
Rachel EstrellaDepartment of Biology, Duke University, Durham, NC 27708, USA.
Chun YeungDepartment of Biology, Duke University, Durham, NC 27708, USA.
Yu-Chieh David ChenDepartment of Biology, New York University, New York, NY 10003, USA.ORCID 0000-0002-2597-7577
Laura Quintana RioDepartment of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10027, USA.
Khanh M VienDepartment of Biology, Duke University, Durham, NC 27708, USA.
Pelin C VolkanDepartment of Biology, Duke University, Durham, NC 27708, USA.ORCID 0000-0002-0001-0626

Funding

Development and Function of an Adult Locomotion Circuit in DrosophilaR01NS070644 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MANN, RICHARD S · 2010 to 2024
$6.2M
Molecular control of stochastic color vision circuit assemblyK99EY035757 · NEI · NEW YORK UNIVERSITY · PI CHEN, YU-CHIEH DAVID · 2024 to 2025
$309k
Coordination and propagation of cell fate choice in neural circuit assemblyF32EY032750 · NEI · NEW YORK UNIVERSITY · PI CHEN, YU-CHIEH · 2021 to 2023
$213k
NEI NIH HHS F32 EY032750NEI NIH HHS K99 EY035757NINDS NIH HHS R01 NS070644
6 · The paper itself

Abstract

Over the past decades, many critical molecular players have been uncovered to control distinct steps in olfactory circuit assembly in Drosophila. Among these, multi-member gene families of cell surface proteins are of interest because they can act as neuron-specific identification/recognition tags in combinations and contribute to circuit assembly in complex brains through their heterophilic or homophilic interactions. Recently, a multi-protein interactome has been described between the Beat and Side families of IgSF proteins. Here, we use the publicly available single-cell RNA-seq datasets and newly generated gene trap transgenic driver lines to probe the

Indexed as

Beaten pathDrosophilaneural developmentolfactory circuitSidestep

Identifiers

PMID40502011
PMCPMC12157644

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.