Evidence map›Paper›PMID 40501842›Full record

ArticlebioRxiv : the preprint server for biology2025

Deep Coverage and Extended Sequence Reads Obtained with a Single Archaeal Protease Expedite

Tatiana M Shamorkina, Laura Pérez Pañeda, Tereza Kadavá, Douwe Schulte, Patrick Pribil, Sibylle Heidelberger, Allison Michele Narlock-Brand, Steven M Yannone, Joost Snijder, Albert J R Heck

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Tatiana M ShamorkinaBiomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Padualaan 8, Utrecht 3584 CH, the Netherlands and Netherlands Proteomics Center, Padualaan 8, Utrecht 3584 CH, the Netherlands.
Laura Pérez PañedaBiomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Padualaan 8, Utrecht 3584 CH, the Netherlands and Netherlands Proteomics Center, Padualaan 8, Utrecht 3584 CH, the Netherlands.
Tereza KadaváBiomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Padualaan 8, Utrecht 3584 CH, the Netherlands and Netherlands Proteomics Center, Padualaan 8, Utrecht 3584 CH, the Netherlands.
Douwe SchulteBiomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Padualaan 8, Utrecht 3584 CH, the Netherlands and Netherlands Proteomics Center, Padualaan 8, Utrecht 3584 CH, the Netherlands.
Patrick PribilSCIEX, 71 Four Valley Drive, Concord, ON, Canada L4K 4V8.
Sibylle HeidelbergerSCIEX, UK Alderley Park, 21 Mereside, Macclesfield UK SK10 4TG.
Allison Michele Narlock-BrandCinder Biological, Inc., San Leandro, California 94577, United States.
Steven M YannoneCinder Biological, Inc., San Leandro, California 94577, United States.
Joost SnijderBiomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Padualaan 8, Utrecht 3584 CH, the Netherlands and Netherlands Proteomics Center, Padualaan 8, Utrecht 3584 CH, the Netherlands.ORCID 0000-0002-9310-8226
Albert J R HeckBiomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Padualaan 8, Utrecht 3584 CH, the Netherlands and Netherlands Proteomics Center, Padualaan 8, Utrecht 3584 CH, the Netherlands.ORCID 0000-0002-2405-4404

Funding

Novel ultra-stable enzymes and methods for proteomicsR44GM128540 · NIGMS · CINDER BIOLOGICAL, INC. · PI YANNONE, STEVEN MICHAEL · 2020 to 2021
$1.7M
NIGMS NIH HHS R44 GM128540
6 · The paper itself

Abstract

The ability to sequence proteins without reliance on a genomic template defines a critical frontier in modern proteomics. This approach, known as

Identifiers

PMID40501842
PMCPMC12154832

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.