Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
16 authors.
Ana T López-JiménezLondon School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, United Kingdom.ORCID 0000-0002-0289-738X
Fabien ThéryVIB-UGent Center for Medical Biotechnology, VIB, Technologiepark-Zwijnaarde 75, 9052 Ghent, Belgium.ORCID 0000-0001-5007-0371
Kathryn WrightLondon School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, United Kingdom.ORCID 0000-0001-6508-3386
Hannah PainterLondon School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, United Kingdom.ORCID 0000-0003-0445-7473
Shelby T HoffmeisterDepartment of Molecular Microbiology and Immunology, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, Oregon 97239, United States of America.
Lucas JarcheDepartment of Microbiology and Immunology, Dalhousie University. Sir Charles Tupper Medical Building, 5850 College Street, B3H 4R2 Halifax, Nova Scotia, Canada.
Jeremy BenjaminDepartment of Microbiology and Immunology, Dalhousie University. Sir Charles Tupper Medical Building, 5850 College Street, B3H 4R2 Halifax, Nova Scotia, Canada.
Gerbrand J van der Heden van NoortDepartment of Cell and Chemical Biology, Leiden University Medical Centre, Einthovenweg 20, 2333 ZC Leiden, The Netherlands.ORCID 0000-0001-5955-6431
Dominik BrokatzkyLondon School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, United Kingdom.ORCID 0000-0001-6304-3292
Margarida C GomesLondon School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, United Kingdom.ORCID 0000-0001-9656-6145
Sydney L MilesLondon School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, United Kingdom.ORCID 0000-0003-2291-4105
Damián Lobato-MárquezLondon School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, United Kingdom.ORCID 0000-0002-0044-7588
John RohdeDepartment of Microbiology and Immunology, Dalhousie University. Sir Charles Tupper Medical Building, 5850 College Street, B3H 4R2 Halifax, Nova Scotia, Canada.ORCID 0000-0002-8569-3760
Jonathan N PrunedaDepartment of Molecular Microbiology and Immunology, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, Oregon 97239, United States of America.ORCID 0000-0002-0304-4418
Francis ImpensVIB-UGent Center for Medical Biotechnology, VIB, Technologiepark-Zwijnaarde 75, 9052 Ghent, Belgium.ORCID 0000-0003-2886-9616
Serge MostowyLondon School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, United Kingdom.ORCID 0000-0002-7286-6503
Funding
Exploiting bacterial effector proteins to study human ubiquitin signalingR35GM142486 · NIGMS · OREGON HEALTH & SCIENCE UNIVERSITY · PI Jonathan N Pruneda · 2021 to 2026
$2.6M
NIGMS NIH HHS R35 GM142486Wellcome Trust
6 · The paper itself
Abstract
Host cells contest invasion by intracellular bacterial pathogens with multiple strategies that recognise and / or damage the bacterial surface. To identify novel host defence factors targeted to intracellular bacteria, we developed a versatile proximity biotinylation approach coupled to quantitative mass spectrometry that maps the host-bacterial interface during infection. Using this method, we discovered that intracellular
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Proximity biotinylation at the host- · full record | OpenQuestion