Evidence map›Paper›PMID 40501816›Full record

ArticlebioRxiv : the preprint server for biology2025

Let-7b-5p loaded Mesenchymal Stromal Cell Extracellular Vesicles reduce

Sharanya Sarkar, Roxanna Barnaby, Amanda Nymon, Lily A Charpentier, Lily Taub, Matthew J Wargo, Daniel J Weiss, Tracey L Bonfield, Bruce A Stanton

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Sharanya SarkarDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, NH, USA.
Roxanna BarnabyDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, NH, USA.
Amanda NymonDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, NH, USA.
Lily A CharpentierDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, NH, USA.
Lily TaubDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, NH, USA.
Matthew J WargoDepartment of Microbiology and Molecular Genetics, University of Vermont, Burlington, VT, USA.
Daniel J WeissDepartment of Medicine, University of Vermont, Burlington, VT, USA.
Tracey L BonfieldNational Center for Regenerative Medicine, Case Western Reserve University, Cleveland, OH, USA.
Bruce A StantonDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, NH, USA.

Funding

Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Fred W Kolling IV · 1985 to 2026
$91.3M
Zhao - Proj 2P20GM130454 · NIGMS · DARTMOUTH COLLEGE · PI Jennifer Hong · 2019 to 2026
$27.2M
Vector CoreP30DK065988 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Scott H Randell · 2004 to 2026
$26.5M
Translational Research CoreP30DK117469 · NIDDK · DARTMOUTH COLLEGE · PI DEBORAH A HOGAN · 2018 to 2026
$13.9M
Retrieval, Reprocessing, Normalization and Sharing of Gene Expression and Lung Microbiome Data Sets to Facilitate AI/ML Analysis Studies of Bacterial Lung InfectionsR01HL151385 · NHLBI · DARTMOUTH COLLEGE · PI STANTON, BRUCE A. · 2021 to 2024
$2.4M
Acquisition of the NextSeq2000 Sequencing platform to Increase Next Generation Sequencing Throughput While Reducing Costs at DartmouthS10OD030242 · OD · DARTMOUTH COLLEGE · PI KOLLING IV, FRED W · 2021 to 2021
$321k
Host-Pathogen Interactions in a Cystic Fibrosis Polymicrobial Infection ModelF31HL172440 · NHLBI · DARTMOUTH COLLEGE · PI Lily Charpentier · 2024 to 2026
$149k
NCI NIH HHS P30 CA023108NHLBI NIH HHS F31 HL172440NHLBI NIH HHS R01 HL151385NIDDK NIH HHS P30 DK065988NIDDK NIH HHS P30 DK117469NIGMS NIH HHS P20 GM130454NIH HHS S10 OD030242
6 · The paper itself

Abstract

Cystic Fibrosis (CF) is a multiorgan disease caused by mutations in the

Indexed as

Cystic FibrosisHuman Bronchial Epithelial CellsInflammationMesenchymal Stromal Cell Extracellular VesiclesPseudomonas aeruginosa biofilms

Identifiers

PMID40501816
PMCPMC12154590

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.