Evidence map›Paper›PMID 40501806›Full record

ArticlebioRxiv : the preprint server for biology2025

Methicillin-Resistant

Dongzhu Ma, Rekha Arya, Beth Ann Knapick, Nadine Sadaka, Jewelia Rempuszewski, Claudette Moul, Jonathan B Mandell, Neel B Shah, James B Doub, Charlie Gish and 7 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors.

Dongzhu MaArthritis and Arthroplasty Design Laboratory, Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA, USA.
Rekha AryaArthritis and Arthroplasty Design Laboratory, Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA, USA.
Beth Ann KnapickArthritis and Arthroplasty Design Laboratory, Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA, USA.
Nadine SadakaArthritis and Arthroplasty Design Laboratory, Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA, USA.
Jewelia RempuszewskiArthritis and Arthroplasty Design Laboratory, Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA, USA.
Claudette MoulArthritis and Arthroplasty Design Laboratory, Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA, USA.
Jonathan B MandellDepartment of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, USA.
Neel B ShahDepartment of Internal Medicine, Division of Infectious Disease, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
James B DoubDivision of Clinical Care and Research, Institute of Human Virology, University of Maryland, Baltimore, MD, USA.
Charlie GishArthritis and Arthroplasty Design Laboratory, Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA, USA.
Dana ParkerArthritis and Arthroplasty Design Laboratory, Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA, USA.
Stefanie A SydlikDepartment of Chemistry, Carnegie Mellon University, Pittsburgh, PA, USA.
Hunter WoodDepartment of Chemistry, Carnegie Mellon University, Pittsburgh, PA, USA.
Vaughn S CooperDepartment of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0001-7726-0765
Anthony R RichardsonDepartment of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA, USA.
Robert M Q ShanksDepartment of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, USA.
Kenneth L UrishArthritis and Arthroplasty Design Group, The Bone and Joint Center, Magee-Womens Hospital of the University of Pittsburgh Medical Center; Department of Orthopaedic Surgery, Department of Bioengineering, and Clinical and Translational Science Institute, University of Pittsburgh, Pittsburgh, PA, 15219.

Funding

The Role of Teichoic Acid Glycosylation in Phage Activity and Selection in an Ongoing FDA Phase II/III Clinical Study of Bacteriophage Therapy in Chronic Periprosthetic Joint InfectionR01AR082167 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DOUB, JAMES B., URISH, KENNETH L · 2022 to 2025
$1.6M
The Role of Biofilm Formation in Antibiotic Tolerant Periprosthetic Joint InfectionR03AR077602 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI URISH, KENNETH L · 2021 to 2022
$158k
NIAMS NIH HHS R01 AR082167NIAMS NIH HHS R03 AR077602
6 · The paper itself

Abstract

Methicillin resistant

Indexed as

Caseinolytic protease P (clpP)mecAMethicillin-resistant Staphylococcus aureus (MRSA)Penicillin-binding protein 2a (PBP2a)rpoBWall teichoic acid (WTA)β-lactam antibiotics

Identifiers

PMID40501806
PMCPMC12154675

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.