Evidence map›Paper›PMID 40501750›Full record

ArticlebioRxiv : the preprint server for biology2025

Heat-off responses of epidermal cells sensitize

Jiro Yoshino, Avery Chiu, Takeshi Morita, Chang Yin, Federico M Tenedini, Takaaki Sokabe, Kazuo Emoto, Jay Z Parrish

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jiro YoshinoDepartment of Biology, University of Washington, Campus Box 351800, Seattle, WA 98195, USA.ORCID 0000-0001-9761-4882
Avery ChiuDepartment of Biology, University of Washington, Campus Box 351800, Seattle, WA 98195, USA.
Takeshi MoritaLaboratory of Neurogenetics and Behavior, The Rockefeller University, 1230 York Avenue, New York, NY 10065.ORCID 0000-0002-8570-6744
Chang YinDepartment of Biology, University of Washington, Campus Box 351800, Seattle, WA 98195, USA.
Federico M TenediniDepartment of Biology, University of Washington, Campus Box 351800, Seattle, WA 98195, USA.ORCID 0000-0003-2274-0424
Takaaki SokabeThermal Biology Group, Exploratory Research Center on Life and Living Systems, National Institutes of Natural Sciences, Okazaki, Japan.ORCID 0000-0003-1280-9424
Kazuo EmotoDepartment of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033 Japan.ORCID 0000-0003-4194-801X
Jay Z ParrishDepartment of Biology, University of Washington, Campus Box 351800, Seattle, WA 98195, USA.ORCID 0000-0002-0656-9148

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Structural and functional coupling of epidermis to somatosensory neurons in DrosophilaR01NS076614 · NINDS · UNIVERSITY OF WASHINGTON · PI BAUTISTA, DIANA MICHELE, PARRISH, JAY Z · 2011 to 2023
$4.2M
Identification of proteins that structurally couple epidermal cells to somatosensory neuronsR21NS125795 · NINDS · UNIVERSITY OF WASHINGTON · PI PARRISH, JAY Z, ROGERS, STEPHEN · 2021 to 2021
$442k
NIH HHS P40 OD018537NINDS NIH HHS R01 NS076614NINDS NIH HHS R21 NS125795
6 · The paper itself

Abstract

Perception of external thermal stimuli is critical to animal survival, and although an animal's skin is the largest contact surface for thermal inputs, contributions of skin cells to noxious temperature sensing have not been extensively explored. Here, we show that exposure to heat transiently sensitizes

Indexed as

epidermisnociceptionsensitizationsomatosensory neuronthermosensation

Identifiers

PMID40501750
PMCPMC12157477

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.