Evidence map›Paper›PMID 40501704›Full record

ArticlebioRxiv : the preprint server for biology2025

A cross-species rescue by mating method to interrogate gene essentiality across the

Taylor K Wang, Abigail Keller, Omar Kunjo, Maitreya J Dunham

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Taylor K WangDepartment of Genome Sciences, University of Washington, Seattle, WA, USA.
Abigail KellerDepartment of Genome Sciences, University of Washington, Seattle, WA, USA.
Omar KunjoDepartment of Genome Sciences, University of Washington, Seattle, WA, USA.
Maitreya J DunhamDepartment of Genome Sciences, University of Washington, Seattle, WA, USA.ORCID 0000-0001-9944-2666

Funding

Comparative Functional Genomics of YeastR01HG010378 · NHGRI · STANFORD UNIVERSITY · PI DUNHAM, MAITREYA J, SHERLOCK, GAVIN J · 2019 to 2022
$2.3M
NHGRI NIH HHS R01 HG010378
6 · The paper itself

Abstract

The field of budding yeast research has long been empowered by the vast array of genetic tools and community resources available. Rescue by mating is one useful tool that entails mating of meiotic spores directly post-germination. This minimal cell division mating process facilitates mating based screens studying the effects of otherwise haploid lethal gene deletions. In this study, we describe the successful application of rescue by mating across two different

Identifiers

PMID40501704
PMCPMC12157416

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.