Evidence map›Paper›PMID 40501684›Full record

ArticlebioRxiv : the preprint server for biology2025

A covalent recognition strategy enables conspecific mate identification.

Sukjin S Jang, Sanjana Mandala, Hanjie Jiang, Xiao Zhang, Phillip A Cole, Josefina Del Mármol

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sukjin S JangDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, US.
Sanjana MandalaDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, US.
Hanjie JiangDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, US.
Xiao ZhangDepartment of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, US.
Phillip A ColeDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, US.
Josefina Del MármolDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, US.ORCID 0000-0003-2715-0482

Funding

Elucidating the structural determinants of odor specificity in insect olfactory receptorsR00DC019401 · NIDCD · HARVARD MEDICAL SCHOOL · PI DEL MARMOL, JOSEFINA INÉS · 2022 to 2024
$747k
NIDCD NIH HHS R00 DC019401
6 · The paper itself

Abstract

The olfactory system can detect an uncountable number of volatile molecules while retaining the ability to discriminate amongst very similar ones. We identified a unique mechanism employed by insect odorant receptors to discriminate amongst pheromones, chemical communication signals that orchestrate courtship and mating behavior. By coupling cryogenic electron microscopy (cryo-EM) and functional mutagenesis, we find that males of the silkmoth

Identifiers

PMID40501684
PMCPMC12157555

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.