Evidence map›Paper›PMID 40501610›Full record

ArticlebioRxiv : the preprint server for biology2025

The RNA-binding protein TRIM71 is essential for hearing in humans and mice and regulates the timing of auditory sensory organ development.

Xiao-Jun Li, Lin Li, Charles Morgan, Phan Q Duy, Lale Evsen, Le T Hao, Roxane Machavoine, Kahina Belhous, Sylvain Ernest, Françoise Denoyelle and 9 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

Xiao-Jun Li
Lin Li
Charles Morgan
Phan Q Duy
Lale Evsen
Le T Hao
Roxane Machavoine
Kahina Belhous
Sylvain Ernest
Françoise Denoyelle
Cyril Mignot
Frederic Brioude
Marine Parodi
He Huang
Prathamesh T Nadar Ponniah
Waldemar Kolanus
Kristopher T Kahle
Sandrine Marlin
Angelika DoetzlhoferORCID 0000-0002-7424-2112

Funding

Modulation of Choroid Plexus Immuno-secretory Function to Restore Cerebrospinal Fluid Homeostasis in HydrocephalusR01NS109358 · NINDS · YALE UNIVERSITY · PI Kristopher T. Kahle · 2018 to 2026
$2.4M
The role of supporting cell de-differentiation in cochlear hair cell regenerationF31DC020882 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI MORGAN, CHARLES · 2022 to 2024
$143k
NIDCD NIH HHS F31 DC020882NINDS NIH HHS R01 NS109358
6 · The paper itself

Abstract

The RNA-binding protein TRIM71 is essential for brain development, and recent genetic studies in humans have identified

Identifiers

PMID40501610
PMCPMC12154870

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.